CBD vs. THC: Understanding the Key Differences

CBD vs. THC: Understanding the Key Differences


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  • Source: Microbioz India`

  • Date: 08 Feb,2024

Cannabidiol, known as CBD, and tetrahydrocannabinol, abbreviated THC, are some of the most known cannabinoids in cannabis. They have similarities but also have different legal definitions, consequences and potential uses in medicine.

Chemical Structure: THC Vs CBD

  1. THC and CBD are both types of cannabinoids that can be found in the marijuana plant.
  2. THC is a psychoactive component which alters your mood hence causing a feeling of “high”.
  3. CBD has no any psychoactive impact therefore it does not produce high effects at all.

Psychoactive Effects:

  1. CB1 receptors in the brain bind to THC like the endocannabinoids thereby causing their psychoactivity and highness feeling when used.
  2. On the other hand, CBD is associated with low affinity for CB1 receptors hence no psychoactivity.

Medical Uses: cbd vs thc

  1. Other therapeutic applications of THC include analgesic efficacy, antiemetic properties, appetite enhancer activity, muscle relaxant capabilities and it could be administered to chemotherapy patients suffering from vomiting among others. It is commonly used for various conditions such as chronic pain, multiple sclerosis and chemotherapy-induced vomiting in medical marijuana.
  2. CBD has gained attention due to its potential benefits such as anxiolytic action against anxiety disorders; reduction in pain measured by analgesiometry; suppression of inflammation via inhibition prostaglandin E(2) synthesis; facilitation of sleep via sedation; while maybe treating epilepsy. Oils, capsules or topical forms can be used.

Also read:

CBD Products for Anxiety and OCD: A Comprehensive Review


  1. This is because THC makes people high hence outlawed by many countries across the globe due to this illicit nature at times attracting abuse charges. But there are places where THC is legal for either medical uses or recreational uses based on prevailing regulations.
  2. However according to certain rules CBD derived from hemp plants with less than 0.3% THC content is legal mostly in United States. However, CBD derived from marijuana containing more than 0.3% THC content may have different legal restrictions or even be illegal in some jurisdictions.

Side Effects:

  1. THC can sometimes impair memory, coordination and judgement, causes dry mouth, reddening of the eyes, raises heart rate as well as induce anxiety or paranoia especially when taken in large doses.
  2. While rare, CBD has been reported to cause a few side effects including dizziness. Some people may experience sleepiness and diarrhea.


It’s important for patients considering using any THC or CBD product to speak with their physician first about potential drug interactions because both substances may affect how other medications are metabolized in the body.

Towards the end of this article it will be made clear that while THC and CBD belong to the cannabinoids family found in cannabis plants; they stand apart from each other due to such differences related to their psychotropic effects; medicinal applications such as pain relief and inflammation reduction; legalization issues as well as possible adverse reactions. With its non-psychoactive profile, CBD might offer substantial health benefits without leading to a high sensation which makes it very appealing to people who seek relief without getting intoxicated by THC.

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