Advances in photochemistry for batch and flow Chemical Synthesis

Advances in photochemistry for batch and flow Chemical Synthesis

Overview

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  • Source: Uniqsis

  • Date: 10 Apr,2023

Steve Evans joined Uniqsis in 2017 to take on the role of International Sales Manager. Steve has a broad expertise of life sciences instrumentation including flow chemistry and microwave assisted organic synthesis. He has a wealth of experience having previously held commercial positions including sales, account development/management, sales team/distributor management, product/business development, global sales & marketing management. Steve has a BSc in chemistry. In January 2019 Steve took on the role of Chief Commercial Officer. Here I am sharing an interesting interaction with Steve Evans.

Can you tell me a little about Uniqsis Ltd, and its product technologies?

Since 2007, Uniqsis has specialised in the design and supply of mesoscale continuous flow chemistry systems for a wide range of applications in chemical and pharmaceutical research. The company’s aim is to make flow chemistry easily accessible to both novices and experienced users.

Uniqsis’ product line has evolved over the years starting with the FlowSyn Multi Experiment System for running small numbers of reaction optimization experiments through to today to a high throughput reaction optimization flow chemistry system running large numbers of compound library synthesis called the Auto Loop Filling system or Auto LF.

Steve Evans Chief Commercial officer, Uniqsis

With growing recognition of the benefits of photochemistry synthesis, we have in the last few years introduced a range of high performance photoreactors for standalone batch use and integration with our existing flow chemistry systems.

What are the main benefits of Photochemistry to researchers?

Typical benefits of photochemical synthesis include efficient irradiation of the reaction, easy reaction scalability, high reproducibility, excellent reaction selectivity and the ability to perform multiphase chemistry.

Safety is of paramount importance to any chemist undertaking photochemical reactions. To maximise safety, all our photoreactors have been designed to operate without any light leakage. Consequently, they do not require a tinted or light-tight enclosure. Safety interlocks are also fitted to eliminate the possibility of accidental exposure to high intensity LED light.

Please tell me about the photochemistry products you offer, their benefits and some applications they have solved?

Uniqsis offers the widest range of photochemistry products of any flow chemistry company – they are versatile, safe and scalable. Our range of Photo Flow Reactors, eliminate problems associated with traditional batch methods enabling synthetic chemists to routinely scale-up their photochemistry reactions from milligrams to several kilograms per day.

The Uniqsis Borealis is a high intensity LED lamp unit, available in a range of fixed wavelengths that converts the existing Cold Coil standalone coil reactor module into a flow reactor for photochemical applications.

The Photochemistry LED Illuminator has been developed to enable small scale batch optimisation of photochemical reactions followed by scale up using either larger batch reactor vessels or a continuous flow glass plate reactor.

The Uniqsis PhotoSyn is a high-power LED light source for continuous flow applications. Available with a selection of different LED arrays the unit can provide outputs up to 700W from the dedicated programmable power supply. These products give reproducible consistent light penetration, controlled exposure times and precise temperature control enabling the chemist to obtain higher yields and improved selectivity.

Do you have any new photochemical innovations that will come to market in 2023 that you would like to share with our readers?

 Yes, to complement our comprehensive range of flow photoreactors we will be launching an add-on photochemistry batch accessory to the Borealis range of systems. The ‘Solstice’ batch accessory will convert the Borealis system to a batch photochemistry reactor.

The Solstice will comprise of a circular rack holding 12 x 8ml tubes each with an optimal working volume of 0.5 to 5mls. The Borealis lamp unit fits inside the rack of tubes irradiating the glass tubes evenly from the inside. The top of the lamp unit locks into the top of the circular tube holder to eliminate any light leakage and includes a temperature sensor. The Solstice/Lamp Unit will conveniently fit onto any commercial hot plate stirrer of plate diameter 135mm.

How are Uniqsis products sold and supported in the Indian market, will you be attending any local exhibitions this year?

Uniqsis has chosen to work with experienced and knowledgeable local companies in all the main Asia / Pacific markets.

In 2022 we set up a new partnership in India with Ultra Instruments Pvt. Ltd. Ultra Instruments maintain multiple well-equipped facilities located throughout the Indian sub-continent to provide extensive coverage for sales and support activities to its’ customer base.

I am working closely with the team at Ultra to organise a series of seminar/demo tours in various locations in India during 2023.

Can you tell our readers a little bit about yourself and your background in the instrumentation industry?

Steve Evans joined Uniqsis in 2017 to take on the role of International Sales Manager. Steve has extensive experience and broad expertise of life sciences instrumentation including flow chemistry and microwave assisted organic synthesis. He has a wealth of experience having previously held commercial positions including sales, account development/management, sales team/distributor management, product/business development, global sales & marketing management. Steve has a BSc in chemistry. In January 2019 Steve took on the role of Chief Commercial Officer at Uniqsis Ltd.

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