Cell Therapy manufacturing challenges Kumar Jeetendra | July 8, 2024 Cell therapy is a medical breakthrough in addressing various illnesses such as cancer, genetic disorders and immune system related diseases. However, the translation of these therapies from lab to clinical and commercial settings is obstructed by significant manufacturing challenges. This article covers the complexities of cell therapy manufacturing, highlighting some major technical, regulatory and logistical …
The Ultimate Guide to Choosing the Best Hospital Disinfectant in 2024 Kumar Jeetendra | June 4, 2024 Hospitals and other healthcare facilities are on the frontlines in the fight against infectious diseases. They prevent the spread of diseases that could compromise the health of their staffs as well as patients by creating a clean and sterile environment for work. With so many products to choose from how can you make sure you …
Optimizing Pharmaceutical Microbiology:TM Media’s Clean Room Microbial Environmental Sampling Guide Kumar Jeetendra | May 30, 2024 It is important to control or eliminate any microbial contaminants which can have a great effect on production processes, products and finally the consumer when working with pharmaceutical products. For these reasons, environmental monitoring and sampling are essential in order to prevent them from getting out of hand. This process ensures that the manufacturing environment …
Emerging trends in immunotherapy and cancer Kumar Jeetendra | May 30, 2024 Imagine a world where the battle against cancer no longer relies solely on the blunt instruments of chemotherapy and radiation therapy, which, while effective, often come at a high cost to the patient’s wellbeing. Immuno-oncology (IO) therapy has ushered in a new era by harnessing the body’s innate defenses to combat cancer cells and has …
How Multiple Alleles Shape Phenotypic Traits Kumar Jeetendra | May 15, 2024 The connection between genes and traits is one of the most basic concepts in genetics, but often it is more complicated than the simple Mendelian inheritance patterns that many of us learn about first. One way this complexity arises is through having multiple alleles for a single gene. This can significantly affect the phenotypic traits …
Climate Change and Amazon Rainforest Microbial Communities Kumar Jeetendra | May 3, 2024 Climate change is very disruptive to the Amazon rainforest, especially its microbial community. Microbes form part of this unseen world which also represents one of the most important components in the ecological orchestra of any given jungle. These microorganisms are facing an entirely new set environmental factors due to global warming; we shall therefore discuss …
Exploring the Apex Predators of the Microbial World: Viruses and Bacteria Kumar Jeetendra | April 27, 2024 How are viruses different from bacteria apex ? One of the most significant role players in various ecosystems including human bodies, are viruses and bacteria which are two different kinds of microorganisms. Nevertheless, they share some similarities such as small size and ability to cause diseases while still having distinctive characteristics and functions. Bacteria: Cellular …
The Ultimate Guide to Understanding Cue PCR Test Kumar Jeetendra | April 18, 2024 In molecular biology, the LAMP (Loop-Mediated Isothermal Amplification) method is also known as Cue PCR or Loop Amplification. Particularly, it can be used for rapid amplification of nucleic acids which enables detection of specific DNA or RNA sequences under isothermal conditions having a constant temperature mainly 60-65°C. Very important applications including diagnostics, field-based testing and …
Mastering PCR: Tips and Tricks for Successful Amplification Kumar Jeetendra | April 18, 2024 A key tool in molecular biology, the polymerase chain reaction (PCR) amplifies a particular DNA fragment. It’s an effective tool for many uses, such as forensics, genetic research, and diagnosis. Some tips and tricks for getting reliable PCR results are given below: Create high-quality primers: The best primers should be designed in such a way …
Demystifying PCR: How Does it Work? Kumar Jeetendra | April 18, 2024 Do you know Polymerase Chain Reaction (PCR)? PCR is a great tool for amplifying any targeted DNA section. It is widely used in such fields as molecular biology, genetics, medical diagnostics, forensics among others. The polymerase chain reaction (PCR) that may be defined as an artificial replication of DNA occurring in cells within a tube …
Troubleshooting Common Issues in Bacterial Culturing Kumar Jeetendra | April 11, 2024 When handling common problems in bacterial culturing, it is important to use a step-by-step approach for identifying and solving the issues that can come up during the process of culturing. Here are some troubleshooting tips: Contamination: Contamination is among the most typical challenges faced when dealing with bacterial culture. It may result from airborne bacteria, …
The Role of Bioburden in Sterilization Processes Kumar Jeetendra | April 5, 2024 Bioburden is crucial in sterilization processes as it affects the efficiency of sterilization and safety of the products being sterilized. Here is an elaborate illustration on what bioburden does during a sterilization process: Explanation of Bioburden: Prior to sterilisation, bioburden refers to the live microbial population present on a surface or within a substrate, e.g., …
