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Dear Readers,Welcome to the latest issue of The Magazine
Imagine the world of biotechnology – gene editing and synthetic biology – and try to fit Ceratosaurus, the prehistorical predator known for roaming the Jurassic period, in it. Such an attempt would sound peculiar until you realize that evolution and biology based in fossils play an integral part of today’s biotech innovations.
Evolution’s impact is as prevalent in biotechnology as studying ancient DNA or engineering vaccines. Now that we are aware of nature’s ancient guidelines, it is worth pondering how the oldest blueprints can steer some of humanity’s finest scientific accomplishments.
The Ceratosaurus fossil discovered in the late 19th century has always been considered a piece of art, but it’s more than just a pretty fossil – it is part of a larger world of evolutionary scope. By studying such fossils, scientists have been able to understand how species like to evolve, their efficient changing traits, and how with the aid of genetic variations life can effortlessly adapt.
The insights provided by these evolutions give centuries worth of foundational wit for genetic advancement, working in tandem with comparative biology and molecular evolution, which are all pivotal subjects for the modern-day biotech industry.
The “Research and Development” of Nature’s Evolution: Insightfully, nature didn’t have a textbook – it nurtured every life. In fact, every living being had natural forces experimenting on it for eternity, serving as a grand lab for Evolution. But even before history tells us, Biotech era has started exploring Nature’s capabilities.
The genetic make-up of older organisms is retained in modern day creatures. This enables the use of model organisms, such as zebrafish or fruit flies, to study pathological human conditions.
The understanding of how various characteristics are selected with time contributes to drug resistance mechanism development for cancer therapies or responses to pandemics.
The process of exchanging genes among species (mostly seen in bacteria) gave birth to technologies such as CRISPR-Cas9, which started off as a microbial defense system and is now used to modify genes.
Using bacteria as an example, we can discover other useful technologies inspired by biological concepts.
This gene-editing technology has been unveilled in bacteria, CRISPR No Microbe will ever evolve without nurturing proper viruses. Today, defending systems such as gene editing revolutionizes medicine, agriculture, and politics even at a climatic changeóttir.
With the aid of a test tube, scientists are able to perform guided selections on proteins and enzymes through a process referred to as mimicking natural selection. The step-by-step evolution guided by a direction has won a nobel prize, which sharply developed green chemo, efficient vaccinations, better pharmaceuticals, and many more.
Taking an extensive look on the DNA sequences of species, scientists are able to determine the markers which indicate, disease, targeted genes that need editing, and even pathways that help in developing drugs.
Experts now have the capability to reconstruct long extinct proteins, dating back to the Jurassic period, for the sake of studying and analyzing stability and functionality. Their use in the industrial setting can lead to the creation of more resilient enzymes.
What comes to mind is why a research lab and pharma company should care about a creature such as Ceratosaurus and evolution.Evolution is very much meaningful, as it provides a context in which a biological system changes, adapts, and interact with one another. With the help of this lens in vaccine and drug development, accuracy, efficiency, and innovation increase drastically.
