Emerging trends in immunotherapy and cancer

Emerging trends in immunotherapy and cancer


  • Post By : Kavita Iyer , Scientist, ACS International India Pvt. Ltd.

  • Source: ACS International India Pvt. Ltd.

  • Date: 30 May,2024

Imagine a world where the battle against cancer no longer relies solely on the blunt instruments of chemotherapy and radiation therapy, which, while effective, often come at a high cost to the patient’s wellbeing. Immuno-oncology (IO) therapy has ushered in a new era by harnessing the body’s innate defenses to combat cancer cells and has already proven effective in treating bladderbreast, and colorectal cancers, among others.

As with any cutting-edge field, the landscape of IO therapy is vast and multifaceted. It stretches beyond a singular approach, encompassing a rich tapestry of methodologies and strategies aimed at augmenting our immune response. From immune-boosting drugs that galvanize our body’s defenses to monoclonal antibodies targeting specific cancer-related proteins, immunotherapy for cancer is a dynamic arena where innovation knows no bounds.

We mined the extensive CAS Content Collection™, the largest human-compiled multi-disciplinary database of documents and substances, to uncover the emerging trends and concepts in this broad and rapidly progressing field. There has been a steady increase in immunotherapy interest for cancer recently. (Figure 1).

Figure 1. Overall growth in publications (A) and increase in commercial interest (B) in immuno-oncology.

Exploring emerging trends in cancer immunotherapy

A thorough analysis of data sourced from the CAS Content Collection in cancer immunotherapy led us to a substantial dataset comprising over 350,000 publications, encompassing both journals and patents dedicated to this field. This analytical endeavor demanded a meticulous approach, beginning with subject matter experts (SMEs) crafting a highly specific search query. This was followed by Natural Language processing, allowing the identification of phrases and rigorous manual scrutiny by our SMEs to fine-tune those phrases. Ultimately, the carefully curated set of phrases was the foundation for deriving insights into the growth patterns of publications and citations from 2003 to 2022 — a CAS TrendScape®.  (Figure 2).

Figure 2. CAS TrendScape® map of growth patterns in immunotherapy publications for cancer.


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