Drug discovery pipeline to exploit transcription factors for cancer therapy Kumar Jeetendra | July 21, 2020 Cancer is a major cause of death and among the most complicated challenges to contemporary medication. By employing cutting-edge technologies that precisely measure the effects of candidate targets and drugs on the fundamental process of transcription, the new start-up firm QUANTRO Therapeutics tries to radically change the precision and range of cell-based drug screening. QUANTRO’s …
Dotmatics collaborates with LabVoice Kumar Jeetendra | November 14, 2020 Dotmatics Ltd, a scientific informatics software and services company that is driving the automation of laboratory data workflows for scientific discovery and innovation research, today announced a new partnership with LabVoice to provide R&D scientists with the ability to record, access, and track data within an electronic laboratory notebook (ELN) using hands-free voice-assisted technology. The …
IGC analysts get three out of six European Research Council grants Kumar Jeetendra | December 11, 2020 Since the establishment of the European Research Council in 2008, the IGC has secured 17 of the competitive grants (7 Beginning, 8 Consolidator and two Advanced). In 2021, with the beginning of the new grants awarded this month, it will have ten active grants. The year of 2020 marks a total of 327 researchers chosen …
Researchers find out protein that adjusts gene interest to healthy nutrient stages in roundworms Kumar Jeetendra | December 23, 2020 Changing a fertilized egg into a fully functional adult is a complicated endeavor. Cells must split, move, and mature at specific times. Developmental genes control that process, turning on and off at a choreographed way. However, the environment affects development. They discovered a master switch developing worms use to pause growth when nutrients are scarce. …
Study clarifies the impact of getting old on hematopoietic stem cells Kumar Jeetendra | December 25, 2020 By shifting mouse elderly hematopoietic stem cells (aged HSCs) to the environment of young mice (bone marrow niche), it was shown that the pattern of stem cell gene expression was rejuvenated to that of young hematopoietic stem cells. On the other hand, the function of elderly HSCs failed to recover in the young bone marrow …
Research finds new proof about the systems controlling skin repair and regeneration Kumar Jeetendra | January 19, 2021 As the air continues to dry and temperatures drop, the yearly battle against dry hands and skin has officially begun. New research from Northwestern University has discovered new evidence deep within the skin about the mechanisms controlling skin renewal and repair. Skin’s barrier function gives it the unique ability to fight winter woes and keep …
Protein alteration adds to degeneration of neuronal populaces in Huntington’s infection Kumar Jeetendra | February 1, 2021 A study in which UB scientists have taken part states that alterations in the levels of one of those proteins, lamin B1, add to the degeneration of distinct brain neuronal populations in Huntington’s disease. Caused by a mutation in the huntingtin gene, this pathology features involuntary movements, cognitive deficit, and psychiatric disorders, and has no …
Sulforaphane draws out life expectancy and healthspan of C. elegans through insulin/IGF-1 flagging Kumar Jeetendra | February 4, 2021 Aging-US released”Sulforaphane boosts C. elegans longevity and healthspan through DAF- 16/DAF-2 insulin/IGF-1 signaling” which reported that the broccoli-derived isothiocyanate sulforaphane inhibits inflammation, oxidative stress and cancer, but its impact on healthspan and longevity are unclear. The writers used the C. elegans nematode version and fed the wildtype and 9 mutant strains ±sulforaphane. Sulforaphane increased the …
Novel device can add or eliminate sugar from proteins Kumar Jeetendra | March 12, 2021 Sugar has been called “evil,” “toxic,” and “poison.” But the body needs sugars, also. Sugar molecules help cells recognize and fight germs and viruses, shuttle proteins from cell to cell, and make sure those proteins function. Too much or too small can give rise to a range of maladies, including neurodegenerative diseases like Alzheimer’s, diabetes, …
Intense openness of lung tissue to vape airborne lesserly affects gene expressionthan cigarette smoke Kumar Jeetendra | March 21, 2021 A new peer-reviewed study published in the journal Toxicological Research & Application reveals acute exposure of a 3D human bronchial tissue model to e-cigarette aerosol has minimal impact on gene expression in contrast to smoke from combustible cigarettes. The study included sub-cytotoxic vulnerability to cells in a 3D human bronchial model (MucilAirTM) to nicotine-containing vape …
New examination reveals insight into complex brain measure that learns and structure new memories Kumar Jeetendra | April 19, 2021 Making memories involves over seeing friends or taking photos. How neurons do so –reaching out arm-like dendrites to communicate with other neurons–requires a ballet of genes, signaling molecules, cellular scaffolding and protein-building machinery. A new study from scientists at Scripps Research and the Max Planck Florida Institute for Neuroscience finds a fundamental role for one …
New testing protocols for SARS-CoV-2 can handle a huge number of tests inside 48 hours Kumar Jeetendra | May 25, 2021 Researchers in the Vienna BioCenter designed a testing protocol for SARS-CoV-2 that can process tens of thousands of samples in less than 48 hours. The method, called SARSeq, is printed in the journal Nature Communications and might be adapted to many more pathogens. The COVID-19 pandemic has lasted more than a year and continues to …
