Researcher Unlock Anti Aging Mystery Of Pomegranate

Researcher Unlock Anti Aging Mystery Of Pomegranate


  • Post By : Kumar Jeetendra

  • Source: Ecole Polytechnique Federale de Lausanne

  • Date: 12 Jul,2016

Researcher from Ecole Polytechnique Fédérale de Lausanne done a brilliant job to unlock, anti-aging mystery of pomegranate fruit. The researcher identified compounds in pomegranate that helps to prevent muscle cells against the major cause of aging with the help and support of Gut Microflora.

The concern study has recently appeared in the journal Nature Medicine.

The scientists identified a molecule that, all by itself, managed to re-establish the cell's ability to recycle the components of the defective mitochondria: urolithin A. "It's the only known molecule that can relaunch the mitochondrial cleanup process, otherwise known as mitophagy," says Patrick Aebischer, co-author of the study. "It's a completely natural substance, and its effect is powerful and measurable."

According to Chris Rinsch, co-author and CEO of Amazentis, this evolutionary process explains the molecule's effectiveness: "Precursors to urolithin A is found not only in pomegranates, but also in smaller amounts in many nuts and berries. Yet for it to be produced in our intestines, the bacteria must be able to break down what we're eating. When, via digestion, a substance is produced that is of benefit to us, natural selection favors both the bacteria involved and their host. Our objective is to follow strict clinical validations, so that everyone can benefit from the result of these millions of years of evolution."

The research work for better result is underway and no doubt may give hope for treating a number of aging related disorders too in future.

Story source/Credit:  Ecole Polytechnique Fédérale de Lausanne

Journal references:

Dongryeol Ryu, Laurent Mouchiroud, Pénélope A Andreux, Elena Katsyuba, Norman Moullan, Amandine A Nicolet-dit-Félix,Evan G Williams, Pooja Jha, Giuseppe Lo Sasso, Damien Huzard, Patrick Aebischer, Carmen Sandi,Chris Rinsch & Johan Auwerx. Urolithin A induces mitophagy and prolongs lifespan in C. Elegance and increases muscle function in rodents. Nature Medicine, July 2016 DOI: 10.1038/nm.4132

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