Is it safe to take omnicef while pregnant?

Is it safe to take omnicef while pregnant?


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  • Source: Microbioz India

  • Date: 01 Mar,2023

Omnicef, also known as cefdinir, is a cephalosporin antibiotic that is utilised in the treatment of a wide variety of bacterial illnesses. In the United States, the Omnicef brand name has been taken off the market. There is a generic version of Omnicef that can be purchased.

Cefdinir is an extended-spectrum, semisynthetic cephalosporin that can be taken orally in the form of OMNICEF (cefdinir) capsules and OMNICEF (cefdinir) for oral solution. Both of these formulations contain the same active component. Cefdinir is characterised by its chemical formula as [6R-[6α, 7β (Z)]]-7-[[(2-amino-4-thiazolyl) (hydroxyimino)acetyl] amino]3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. Cefdinir is a solid that ranges in colour from white to a little brownish-yellow. It is only sparsely soluble in 0.1 M phosphate buffer with a pH of 7.0, and it is only marginally soluble in dilute hydrochloric acid.


If you have an allergy to cefdinir or other antibiotics that work in a similar way, including Ceftin, Cefzil, Keflex, and others, you should not take Omnicef.

Inform your physician of any known drug allergies you have before beginning treatment with Omnicef (especially penicillin). If you have a history of digestive difficulties or kidney disease, you should also mention that to your doctor.

Take Omnicef for the total amount of time that is recommended by your doctor. It’s possible that your symptoms will go better before the virus is totally gone. Missing doses can also raise the likelihood that you will develop a secondary infection that is resistant to the antibiotics you are taking. An infection that is caused by a virus, such as the common cold or the flu, cannot be treated with cefdinir.

Is it safe to take Omnicef while pregnant?

Taking Omnicef while pregnant The Food and Drug Administration has placed cefdinir in the pregnancy category B. Studies conducted on animals have shown evidence of maternal toxicity, which manifests as a reduction in body weight gain, as well as a reduction in foetal body weight. In human pregnancies, there are no controlled data available. Cefdinir should only be taken during pregnancy if there is a demonstrated and immediate necessity for it.

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Cefdinir was not found to be teratogenic in rats when given orally at doses up to 1000 mg/kg/day (70 times the human dose based on mg/kg/day, 11 times the human dose based on mg/m/day), nor was it found to be teratogenic in rabbits when given orally at doses up to 10 mg/kg/day (0.7 times the human dose based on mg/kg/day, 0.23 times the human dose based on At the maximum tolerable dose of 10 mg/kg per day, maternal toxicity, as measured by a reduction in body weight growth, was found in rabbits; however, this did not result in any negative consequences in the offspring. At a dose of 100 mg/kg/day, the body weight of rat foetuses was shown to decrease, but the body weight of rat offspring was found to decrease at a dose of 32 mg/kg/day. There was no evidence that the exposure had any impact on the reproductive parameters of the mother or the reproductive function, development, or behaviour of the offspring.


  1.  “Cefdinir Monograph for Professionals” American Society of Health-System Pharmacists. Retrieved 23 March 2019.
  2. ^ “Cefdinir Use During Pregnancy” Retrieved 3 March 2019.
  3. ^ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 49X. ISBN 9783527607495.
  4. ^ “The Top 300 of 2020”ClinCalc. Retrieved 7 October 2022.
  5. ^ “Cefdinir – Drug Usage Statistics”ClinCalc. Retrieved 7 October 2022.
  6. ^ “Susceptibility and Minimum Inhibitory Concentration (MIC) Data” (PDF). October 14, 2015. Retrieved 1 October 2015.

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