MMR immunization could offer assurance against COVID-19 Kumar Jeetendra | June 20, 2020 Directing the MMR (measles, mumps, rubella) antibody could fill in as a preventive measure to hose septic aggravation related with COVID-19 disease, state a group of specialists in the current week’s mBio, a diary of the American Society for Microbiology. Long-term colleagues and life partners Dr. Paul Fidel, Jr., Department Chair, Oral and Craniofacial Biology, …
Protein delivered by the human safe framework can emphatically hinder Sars-Cov-2 Kumar Jeetendra | August 3, 2020 A protein produced by the human immune system may strongly inhibit corona viruses, including Sars-Cov-2, the pathogen causing Covid-19. An international team from Germany, Switzerland and the USA successfully showed the LY6E-Protein prevents coronaviruses from causing the illness. “This finding may result in the development of new therapeutic approaches against coronaviruses,” says Professor Stephanie Pfänder …
Examination shows how a protein prevents cells from assaulting their own DNA Kumar Jeetendra | August 20, 2020 Viruses multiply by injecting their DNA into a host cell. Once it passes the intracellular fluid, then this foreign substance triggers a defense mechanism referred to as the cGAS-STING pathway. This, in turn, binds to another protein named Stimulator of Interferon Genes (STING), which induces an inflammatory immune reaction. From time to time, the material …
Study shows tofacitinib medication can fix porousness absconds in the digestive tract Kumar Jeetendra | October 6, 2020 A team of researchers led by biomedical scientist Declan F. McCole in the University of California, Riverside, has found that the medication tofacitinib, also called Xeljanz and approved by the FDA to treat rheumatoid arthritis and ulcerative colitis, can fix permeability defects in the intestine. Study results appear in the Journal of Crohn’s and Colitis. …
Researchers distinguish systems behind inflammasome initiation by fungal pathogens Kumar Jeetendra | December 3, 2020 Researchers at St. Jude Children’s Research Hospital have identified the mechanisms behind inflammasome activation driven by infection with the fungal pathogen Aspergillus fumigatus. Fungal infection, especially with A. fumigatus, is a leading cause of infection-associated deaths in people with compromised immune systems. The work provides clues to a potential therapeutic approach for treating infectious and …
Rapid Viral, Pathogen Characterization RNA-Seq Library Prep Solution launched by Tecan Kumar Jeetendra | December 7, 2020 Tecan has launched the Revelo RNA-Seq kit, offering end-to-end processing of individual samples to enable complete viral RNA-Seq library preparation–including library quantification–in one day. This kit has been developed specifically to deal with the pathogen detection and characterization challenges now faced by laboratories around the world, and is ideally suited to NGS library prep from …
Conceivable new anti-microbial created for drug-resistant pulmonary microorganism Kumar Jeetendra | December 9, 2020 Scientists from Johns Hopkins University and Medicine have developed a potential new antibiotic for a pathogen that is notoriously resistant to drugs and often lethal for people with cystic fibrosis and other lung disorders. The pathogen, called Mycobacterium abscessus, is related to some better-known bacterium that causes tuberculosis and leprosy but has recently emerged as …
Researchers give knowledge on how lung microorganisms secure against attacking microbes Kumar Jeetendra | December 9, 2020 New insight on how bacteria in the lungs protect against invading pathogens has been published today in the open-access eLife journal. The study in mice shows that a strain of lung bacteria called Lactobacillus provides a barrier against Streptococcus pneumoniae (S. pneumoniae) colonisation in animals previously infected with influenza A virus when applied therapeutically following …
Study distinguishes protein as likely restorative objective for leishmaniasis vaccine Kumar Jeetendra | December 12, 2020 According to the results of research led by the Complutense University of Madrid (UCM), among the various strategies deployed by the Leishmania parasite to avoid tripping the human immune system is to trigger the SHP-1 protein. The parasite does this by secreting a molecule capable of interacting with the Mincle receptor expressed by antigen-presenting dendritic …
First enzyme driven biocatalytic creation of nucleic acid structure blocks Kumar Jeetendra | December 15, 2020 Researchers in TU Graz and acib succeed in the first enzyme-driven biocatalytic synthesis of lipoic acid building blocks. This facilitates the development of antiviral agents and RNA-based therapeutics. Because of this COVID 19 pandemic and the related intensive search for therapeutics and vaccines, the chemical substance class of nucleosides is undergoing an enormous increase in …
Digital chest drainage systems could help reduce COVID-19 spread, research show Kumar Jeetendra | December 20, 2020 Pioneering research, which reveals digital chest drains generate and disperse less aerosol generated particles in comparison to traditional water seal systems, has been published in the Seminars in Thoracic and Cardiovascular Surgery journal. The research was led by a group of thoracic consultants from Guy’s and St Thomas’ NHS Foundation Trust — home to one …
Inflammation may add to the determination of C. diff disease, shows study Kumar Jeetendra | January 19, 2021 A new study from North Carolina State University indicates that the inflammation brought on by Clostridioides difficile (C. diff) infection gives the pathogen a two-fold advantage: by both creating an inhospitable environment for competing bacteria and supplying nutrients that enable C. diff to thrive. C. diff is a bacterium that causes diarrhea, often with severe …
