Study: Anti-microRNA sedate essentially lessens miR-92a levels in human peripheral blood Kumar Jeetendra | August 12, 2020 A single intravenous dose of MRG-110, an anti-microRNA drug, significantly reduced miR-92a levels from the blood of healthy humans. “According to documented, promising therapeutic possible, locked nucleic acid (LNA)-based anti-miR-92a was further developed and tested in a first in human analysis,” said Stefanie Dimmeler, PhD, Goethe University, Frankfurt, Germany and coauthors. “MRG-110 caused de-repression of …
Optimised Microplate for SARS-CoV-2 Nucleic Acid Purification Kumar Jeetendra | November 4, 2020 Porvair Sciences has introduced a new 2.2ml 96 deep well plate specifically designed to be fully compatible with the Thermo Scientific™ KingFisher™ range of nucleic acid purification systems. For many labs, up-front sample preparation and handling represents a major bottleneck in their research workflow, as it is largely done manually. Widely used for the nucleic …
First enzyme driven biocatalytic creation of nucleic acid structure blocks Kumar Jeetendra | December 15, 2020 Researchers in TU Graz and acib succeed in the first enzyme-driven biocatalytic synthesis of lipoic acid building blocks. This facilitates the development of antiviral agents and RNA-based therapeutics. Because of this COVID 19 pandemic and the related intensive search for therapeutics and vaccines, the chemical substance class of nucleosides is undergoing an enormous increase in …
