Fat cell hormone upgrades helpful capability of MSC treatment Kumar Jeetendra | July 12, 2020 Mesenchymal stem cells (MSCs) have the potential to differentiate into a range of different cell types, including bone, fat, and muscle cells. But it’s their ability to stimulate the repair of damaged tissue that has captured the interest of researchers worldwide, with MSCs demonstrating therapeutic effects in the treatment of conditions such as heart disease, …
Test mRNA-based COVID-19 immunization evokes defensive safe reactions in animals Kumar Jeetendra | July 25, 2020 Two injections of this vaccine were enough to induce robust immunity, completely preventing SARS-CoV-2 infection in mice. MRNA-based vaccines are all attractive options for protecting against SARS-CoV-2 because they may be quickly designed and manufactured at a huge scale within weeks. Moreover, preclinical studies have shown that mRNA-based vaccines cause potent and broadly protective immune …
Trial ALS drug shows potential to drag out patient endurance Kumar Jeetendra | October 18, 2020 An experimental medicine that was recently shown to slow the progression of the neurodegenerative disease amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease, has now demonstrated the capacity to also prolong patient survival. The findings come from a clinical trial conducted by investigators at the Sean M. Healey & AMG Center for ALS at Massachusetts …
Skin may assist with foreseeing future heart issues Kumar Jeetendra | December 17, 2020 Our skin informs us when we have spent too much time in sunlight or when the dry air of winter has sucked away too much moisture. Now Jefferson researchers find that the skin may also foretell problems unrelated to the protective barrier. An international group of researchers headed by Jouni Uitto, MD, PhD, a Professor …
New comprehension of physical properties of chromatin may show how genome is encoded and decoded Kumar Jeetendra | December 21, 2020 University of Alberta researchers have found an answer to a basic question in genomic biology that has eluded scientists because the discovery of DNA: Over the nucleus of our cells, is the complex package of DNA and proteins called chromatin a solid or a liquid? Previously, fields like biochemistry operated under the premise that chromatin …
Analysts recognize interface among ALS and collection of DNA-RNA hybrids in the genome Kumar Jeetendra | January 13, 2021 Researchers from the University of Seville and the University of Pavia have identified a connection between Amyotrophic Lateral Sclerosis (ALS) and the accumulation of DNA-RNA hybrids in the genome. The accumulation of these hybrids causes increased genomic damage and boosts genetic instability. This finding will make it possible to better understand the molecular basis of …
Pancreatic β cell-inferred exosomal miR-29s control glucose homeostasis Kumar Jeetendra | January 24, 2021 In a new study published in Journal of Extracellular Vesicles, Chen-Yu Zhang’s team at Nanjing University, School of Life Sciences, and Antonio Vidal-Puig’s group at University of Cambridge report that pancreatic β cells secrete miR-29 family members (miR-29s) via exosomes in reaction to high levels of free fatty acids (FFAs). Formerly, Chen-Yu Zhang’s team identified …
Study shows why children of obese moms have inclination to create metabolic illnesses Kumar Jeetendra | January 27, 2021 A Brazilian study published in the journal Molecular Human Reproduction helps understand why overweight mothers often have children with a propensity to develop metabolic disease during their lifetime, according to previous research. According to the authors,”transgenerational transmission of metabolic disorders” may be associated with Mfn2 deficiency in the mother’s oocytes (immature eggs). Mfn2 refers to …
FDA permits advertising of new remedy just device to lessen wheezing and mild sleep apnea Kumar Jeetendra | February 6, 2021 Now, the U.S. Food and Drug Administration approved marketing of a new prescription only device intended to reduce snoring and moderate obstructive sleep apnea. Unlike devices used while patients sleep, this is the first device used while awake that is intended to improve tongue muscle function, which in time helps prevent the tongue from collapsing …
Hydrogel injection could help fix harm to the heart muscle after heart attack Kumar Jeetendra | February 19, 2021 Researchers at CÚRAM, the SFI Research Centre for Medical Devices based at NUI Galway, and BIOFORGE Lab, at the University of Valladolid in Spain, have developed an injectable hydrogel which might help repair and prevent additional damage to the heart muscle following a heart attack occasion. The results of their research have only been published …
Researchers create shape memory polymer to comprehend the advancement of coronary illness Kumar Jeetendra | March 3, 2021 Cardiovascular disease is still the number one cause of death globally. Unfortunately, the heart cannot regenerate new tissue, because the cardiomyocytes, or heart muscle cells, don’t divide after birth. In their paper, published in APL Bioengineering by AIP Publishing, Syracuse researchers developed a shape memory polymer to grow cardiomyocytes. Raising the substance’s temperature from 30 …
Compounds in green and black tea relax blood vessels by activating ion channel proteins Kumar Jeetendra | March 9, 2021 A new study from the University of California, Irvine shows that chemicals in both black and green tea relax blood vessels by activating ion channel proteins in the blood vessel wall. The discovery helps explain the antihypertensive properties of tea and could lead to the design of new blood pressure-lowering medications. Released in Cellular Physiology …
