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According to research publish in “Journal of Clinical Microbiology” a publication of American society of Microbiology, our canine companion may infected by human norovirus, which increases the possibilities of dog-to-human transmission, according to author: Sarah Caddy, VetMB, PhD, MRCVS.
According to Center of Disease Control USA, Norovirus is a cause of food-borne illness in United States.
According to research, some dogs can mount an immune response to human norovirus, said Caddy, who will be a junior research fellow at the University of Cambridge, beginning in August.
"This strongly suggests that these dogs have been infected with the virus. We also confirmed that that human norovirus can bind to the cells of the canine gut, which is the first step required for infection of cells."
Caddy and collaborators performed the latter research using non-infectious human norovirus particles, which consist solely of the virus' outer protein, called the capsid. The capsid is the part of the virus that binds to host cells. By itself, it is non-infectious because it lacks genetic material.(The non-infectious capsid is the basis for a new norovirus vaccine which is being tested in clinical trials, said Caddy).Nonetheless, it is not clear just how much of a problem canine infection and transmission may represent for humans, said Caddy. Despite dogs' apparent susceptibility, the investigators failed to find norovirus in canine stool samples, including those from dogs with diarrhea. They found it in serum samples of only about one seventh of 325 dogs tested.
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