H3N2 vs H1N1: What’s the Difference Anyway?

H3N2 vs H1N1: What’s the Difference Anyway?


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  • Source: Microbioz India

  • Date: 18 Mar,2023

The term “variant” is used to describe influenza viruses that have been detected in humans but are more commonly found in pigs. In July of 2011, influenza A H3N2 variant viruses were discovered in humans for the first time; these viruses are also known as H3N2 viruses since they contain the matrix (M) gene originally found in the 2009 H1N1 pandemic virus. In 2010, the viruses were first discovered in swine in the United States. Twelve H3N2 virus in humans were documented throughout 2011. There were 309 confirmed cases of H3N2 in 2012, the year that saw many outbreaks.

The H1N1 strain of influenza A virus is a contagious respiratory illness that can affect either the upper or lower respiratory systems. Nasal discharge, chills, fever, loss of appetite, and even lower respiratory tract disease can arise from this. The importance of an interdisciplinary team approach to caring for patients with H1N1 influenza is highlighted in this exercise, which discusses the clinical manifestations, diagnostic testing, and treatment options for this virus. H1N1, sometimes known as swine flu, is a kind of influenza that shares genetic similarities with viruses that affect pigs. Instead, the common cold or influenza is widespread throughout seasonal transitions and typically causes no serious health problems.

Symptoms Difference of H3N2 & H1N1

 Common symptoms of H3N2:

H3N2 influenza symptoms are typically similar to those of seasonal influenza. Examples of these are given by the CDC as follows:

  1. Fever or feeling feverish
  2. Cough
  3. Sore throat
  4. Runny or stuffy nose
  5. Muscle or body aches
  6. Headaches
  7. Fatigue
  8. Vomiting and diarrhoea

Common symptoms of H1N1

A viral infection is what causes swine flu, often known as H1N1. Because it is similar to a respiratory ailment that pigs can acquire, it has been given the name “swine flu.” In 2009, a pandemic of H1N1 caused infection in millions of people all across the world. Your annual flu shot is the best way to protect yourself against H1N1 at this time. You can treat it by getting enough of rest, drinking plenty of water, and taking antiviral medication.

The signs and symptoms of the swine flu, also known as H1N1, are extremely similar to those of the common flu. The onset of symptoms can take anywhere from three to five days following initial virus contact. Among the possible symptoms are:

  1. Fever.
  2. Chills.
  3. Cough.
  4. Sore throat.
  5. Body or muscle aches.
  6. Headache.
  7. Fatigue.

Infant and kid symptoms may vary. See a doctor immediately if your infant or young child exhibits any of the following signs:

  1. Trouble breathing.
  2. Trouble waking up.
  3. Not drinking enough fluids.
  4. Fever with rash.


  1. American Academy of Family Physicians. H1N1 Influenza. (https://familydoctor.org/condition/h1n1-influenza/) Accessed 8/5/2022.
  2. Centers for Disease Control and Prevention. 2009 H1N1 Pandemic (H1N1pdm09 virus). (https://www.cdc.gov/flu/pandemic-resources/2009-h1n1-pandemic.html) Accessed 8/5/2022.
  3. Jilani TN, Jamil RT, Siddiqui AH. H1N1 Influenza. (https://www.ncbi.nlm.nih.gov/books/NBK513241/) [Updated 2022 Jul 18]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan. Accessed 8/5/2022.
  4. MedlinePlus. H1N1 Flu (Swine Flu). (https://medlineplus.gov/h1n1fluswineflu.html) Accessed 8/5/2022.

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