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Hence, the sequence of nucleotides in DNA dictates the gene expression or nucleotide sequence of messenger RNA (mRNA). Thus, a genetic code is carried by DNA (deoxyribonucleic acid), which functions as the genetic blueprint of an organism and comprises directives for protein synthesis. The mechanism by which information from DNA is utilized to produce mRNA is known as transcription.
Finally, it can be said that the sequence of nucleotides in mRNA has an essential role to perform in terms of how cellular machinery responsible for protein synthesis translates genetic information from DNA. In cytoplasm, it acts as a template guiding assembly of amino acid polypeptides into proteins, according to the genetic code.