Genotype vs allele: All you need to know Kumar Jeetendra | March 31, 2023 Genotype refers to the score assigned to the specific variant at a certain locus in the genome. It lends itself to symbolic representation. A gene variant might be represented, for instance, as BB, Bb, bb. The precise DNA sequence at a certain location—CC, CT, or TT—can also stand in for a genotype. Genotypes at millions …