New T-cell-based immunization procedure gives more extensive insurance against occasional flu Kumar Jeetendra | September 24, 2020 As Americans begin pulling their sleeves up for an annual flu vaccine, researchers at the University of Wisconsin-Madison have provided new insights into an alternate vaccine approach that provides wider protection against seasonal flu. In a study published in Cell Reports Medicine today (Sept. 22), scientists describe a T-cell-based vaccine strategy that’s effective against multiple …
New initiative identifies key parameters Inherent effective anti-tumor immunity Kumar Jeetendra | October 10, 2020 Neoantigens, tiny markers that arise from cancer mutations, flag cells as cancerous and could be the key to unlocking a new generation of immunotherapies. Targeting the”right” neoantigens – at a cancer vaccine or a cell treatment – has the promise to eliminate a patient’s cancer with minimal side effects. But countless mutations can exist in …
Putatively juvenile dendritic cells may actuate hearty resistant reactions in young children Kumar Jeetendra | January 20, 2021 A study by Ludwig-Maximilians-Universitaet (LMU) in Munich researchers demonstrates that putatively immature dendritic cells found in young children are able to induce strong immune responses. Dendritic cells are a vital component of the innate immune system, which represents the body’s first line of defense against infectious agents and tumor cells. Their job is to trigger …
Antiviral T cells protected, viable as off-the-shelf treatment for painful complication stem cells Kumar Jeetendra | May 2, 2021 Infusion of T cells targeting BKV resulted in rapid responses, with 67.7% of patients seeing a complete or partial improvement in symptoms after 14 days. This increased to 81.6% of patients after 28 days post-infusion. No cases of grade 3 or grade 4 graft versus host disease (GVHD) or other infusion-related toxicities occurred. Addressing a …