Nicotine: Smoking out the truth Kumar Jeetendra | September 9, 2021 Humanity has had a tumultuous history with nicotine, with use of nicotine-rich tobacco for ceremonial and social functions starting as early as 1400 BC, before being introduced to Europe as a medicinal item in the 16th century. In the last hundred years nicotine reached peak popularity, as tobacco use was glamorised through cigarettes, and then …