Pregnancy builds the danger of first-time symptomatic kidney stone Kumar Jeetendra | April 15, 2021 Though researchers have long known that several physiological and anatomical changes occur during pregnancy which could contribute to kidney stone formation, evidence of the connection has been lacking. An observational study that reviewed the medical records for nearly 3,000 female patients from 1984 to 2012 finds that pregnancy increases the risk of a first-time symptomatic …