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    new cGMP plasmid DNA manufacturing facility construction announced by Thermo Fisher

    Thermo Fisher Scientific, the world leader in serving science, today announced the construction of a new cGMP plasmid DNA manufacturing facility in Carlsbad, Calif. The site will expand the company’s clinical and commercial capabilities for cGMP plasmid DNA used as a critical raw material to develop and manufacture cell and gene-based therapies including life-saving cancer

    Automating DNA Extraction for High-Throughput Bacterial Plasmid Purification

    Originally found in bacteria, plasmids are circular DNA fragments that can self-replicate in the cytoplasm. Within prokaryotic cells, these extrachromosomal DNA molecules typically contain genes that promote survival and virulence. The potential of plasmids to drive discovery became apparent when technologies such as restriction enzymes and PCR allowed scientists to cut and paste a DNA