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    plasmid purification

    Automating DNA Extraction for High-Throughput Bacterial Plasmid Purification

    Originally found in bacteria, plasmids are circular DNA fragments that can self-replicate in the cytoplasm. Within prokaryotic cells, these extrachromosomal DNA molecules typically contain genes that promote survival and virulence. The potential of plasmids to drive discovery became apparent when technologies such as restriction enzymes and PCR allowed scientists to cut and paste a DNA