Examination shows how a protein prevents cells from assaulting their own DNA Kumar Jeetendra | August 20, 2020 Viruses multiply by injecting their DNA into a host cell. Once it passes the intracellular fluid, then this foreign substance triggers a defense mechanism referred to as the cGAS-STING pathway. This, in turn, binds to another protein named Stimulator of Interferon Genes (STING), which induces an inflammatory immune reaction. From time to time, the material …
Study uncovers the complex cell mechanism of Ebola Kumar Jeetendra | July 8, 2021 Mount Sinai researchers discovered the intricate cellular mechanisms of Ebola virus. This could help to explain the severe effects on people and provide potential treatment or prevention. The team published a study in mBio that showed how VP24, a protein from the Ebola virus interacts with the double-layered cell membrane (known as the nucleus) and …
Small molecule drug can weaken the triggers of neuroinflammation, preclinical review shows Kumar Jeetendra | September 24, 2021 Neuroinflammation may cause worse outcomes in cases of stroke, injuries to the brain or injury, and can increase the severity of neurodegenerative diseases such as ALS, Parkinson’s, or Alzheimer’s. This suggests that reducing neuroinflammation might be an exciting new method to treat neurological disorders and neuropathic pain caused by neuroinflammation. In a preclinical study , …
