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    First in class drug shows promise in preclinical neuropathic pain trials

    A “ridiculous idea” inspired by ocean submarines has led to the discovery of a non-opioid, first-in-class drug candidate for neuropathic pain. Scientists attached a ‘chemical anchor’ to the anaesthetic drug propofol – avoiding side-effects by preventing it from penetrating the brain, but allowing it to sink into peripheral nerve cell membranes and inhibit the activity