Trial ALS drug shows potential to drag out patient endurance Kumar Jeetendra | October 18, 2020 An experimental medicine that was recently shown to slow the progression of the neurodegenerative disease amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease, has now demonstrated the capacity to also prolong patient survival. The findings come from a clinical trial conducted by investigators at the Sean M. Healey & AMG Center for ALS at Massachusetts …
Study uncovers a quality answerable for anthraquinone synthesis in plants Kumar Jeetendra | November 25, 2020 Anthraquinones are a class of naturally occurring chemicals prized for their medicinal properties, as well as for other programs, including ecologically friendly dyes. Despite broad interest, the mechanism by which plants produce them has remained shrouded in mystery until today. New work from an international group of scientists including Carnegie’s Sue Rhee shows a gene …
Researchers grow first biohybrid fake retina with silk fibroin and retinal cells Kumar Jeetendra | December 13, 2020 An international research led by the Complutense University of Madrid has taken a further step to solve the age-related macular degeneration (AMD)-derived blidness problem with the development of the first biohybrid artificial retina constructed with silk fibroin and retinal cells. The biohybrid retina is a cell therapy for the reconstruction of the damaged retina by …
Analysts recognize interface among ALS and collection of DNA-RNA hybrids in the genome Kumar Jeetendra | January 13, 2021 Researchers from the University of Seville and the University of Pavia have identified a connection between Amyotrophic Lateral Sclerosis (ALS) and the accumulation of DNA-RNA hybrids in the genome. The accumulation of these hybrids causes increased genomic damage and boosts genetic instability. This finding will make it possible to better understand the molecular basis of …
Study subtleties how glutamate flagging functions in the brain to empower neuronal communication Kumar Jeetendra | January 31, 2021 The most powerful substance in the human brain for neuronal communication is glutamate. It’s by far the most abundant, and it’s implicated in all kinds of operations. One of the most amazing is the slow restructuring of neural networks because of memory and learning acquisition, a process called synaptic plasticity. Glutamate is also of deep …
Small molecule drug can weaken the triggers of neuroinflammation, preclinical review shows Kumar Jeetendra | September 24, 2021 Neuroinflammation may cause worse outcomes in cases of stroke, injuries to the brain or injury, and can increase the severity of neurodegenerative diseases such as ALS, Parkinson’s, or Alzheimer’s. This suggests that reducing neuroinflammation might be an exciting new method to treat neurological disorders and neuropathic pain caused by neuroinflammation. In a preclinical study , …
