Scientists find uncommon hereditary disorder that influences the brain, heart and facial highlights Kumar Jeetendra | January 21, 2021 Researchers at the National Institutes of Health have discovered a new genetic disorder characterized by developmental delays and malformations of the brain, heart and facial features. Named linkage-specific-deubiquitylation-deficiency-induced embryonic defects syndrome (LINKED), it is caused by a mutated version of the OTUD5 gene, which interferes with key molecular actions in embryo development. The findings indicate …
Diphtheria is developing to get antibiotic-resistant safe and could prompt vaccine escape Kumar Jeetendra | March 8, 2021 Diphtheria – a comparatively easily-preventable infection – is evolving to become immune to a range of types of antibiotics and in the future could lead to vaccine escape, warn an international group of researchers in the UK and India. The researchers, led by scientists at the University of Cambridge, say that the impact of COVID-19 …
Mosquito protein study could prompt therapeutics against dangerous viruses Kumar Jeetendra | March 11, 2021 The researchers found that AEG12 works by destabilizing the viral envelope, breaking its protective covering. Although the protein doesn’t affect viruses that don’t have an envelope, such as the ones that cause pink eye and bladder ailments, the findings could lead to therapeutics against viruses which affect millions of people around the world. The research …
Researcher find a gene mutation connected to schizophrenia Kumar Jeetendra | March 24, 2021 Researchers at The Feinstein Institutes for Medical Research, in collaboration with Columbia University, have identified a gene mutation that could result in schizophrenia, a chronic brain disease that affects nearly 1 percent of the planet’s inhabitants. The findings, published in today in Neuron, could lead to novel treatment strategies. The research group, headed by Todd …
Researchers discover proof that SARS-CoV-2 infects cells in the mouth Kumar Jeetendra | March 25, 2021 An international group of scientists has discovered evidence that SARS-CoV-2, the virus that causes COVID-19, infects cells in the mouth. While it’s well known that the upper airways and lungs are primary sites of SARS-CoV-2 disease, there are clues the virus can infect cells in different parts of the body, like the digestive system, blood …
Drug-discovery collaboration discovers potential new antimalarial drug candidates Kumar Jeetendra | April 23, 2021 Potential new antimalarial drug candidates are being developed through an protracted drug-discovery collaboration between Australian medical research institute WEHI and Janssen Pharmaceutica NV. The collaboration was facilitated by Johnson & Johnson Innovation. A collaborative research team discovered compounds with antimalarial activity within a collection of 80,000 drug-like molecules at the Janssen Jump-stARter Compound Library, a …
NIAID sets up a clinical research organization to improve comprehension of child asthma Kumar Jeetendra | April 25, 2021 This nationwide network will conduct observational studies and clinical trials to improve understanding of asthma and develop prevention and treatment approaches tailored to children of low-income families residing in urban communities. NIAID plans to provide approximately $70 million over seven years to support the CAUSE network. This new initiative expands and extends NIAID’s long-standing attempts …
Researchers develop experimental direct-acting antiviral treatment to treat COVID-19 Kumar Jeetendra | May 18, 2021 An international team of scientists from the Menzies Health Institute Queensland (MHIQ) at Griffith University and from City of Hope, a research and treatment center for cancer, diabetes and other life-threatening diseases in the U.S., have developed an experimental direct-acting antiviral therapy to treat COVID-19. Conventional antivirals reduce symptoms and help people recover earlier. Examples …
New medication like compound could adequately hinder a critical step in malaria parasite life cycle Kumar Jeetendra | May 19, 2021 Researchers at the Francis Crick Institute and the Latvian Institute of Organic Synthesis have designed a drug-like compound which effectively blocks a vital step in the malaria parasite life cycle and are working to develop this compound into a potential first of its type malaria treatment. While drugs and mosquito control have reduced levels of …
Growing genomic research into different ancestries yields more and better outcomes Kumar Jeetendra | June 1, 2021 Currently published in Nature Genetics, their findings demonstrate that expanding research into different ancestries yields more and better results, in addition to ultimately benefitting global patient care. Up to now nearly 87 percent of genomic research of the type was conducted in Europeans. The global study team examined data across a wide assortment of cohorts, …
MRI screening and designated biopsies could diminish overdiagnoses of prostate malignant growth Kumar Jeetendra | July 10, 2021 Many countries do not have nationwide prostate-cancer screening. Current methods lead to overdiagnoses, unnecessary biopsies, and unnecessary biopsies. Researchers at Karolinska Institutet, Sweden, have published a new study in The New England Journal of Medicine. It shows that targeted biopsies and magnetic resonance imaging (MRI), could reduce overdiagnoses by up to half. These results were …
Researchers develop AI-based model to analyze cardiovascular illnesses and diabetes Kumar Jeetendra | August 14, 2021 Scientists from South Ural State University (SUSU), along with colleagues from France, Spain, and Egypt, have created a model that can be used to diagnose cardiovascular diseases and diabetes more effectively using artificial intelligence and Internet of Things technology. The Russian Ministry of Science and Higher Education supported this work. In an article published in …
