Jubilant Therapeutics reports preclinical information of double LSD1 and HDAC6 at AACR 2020 Kumar Jeetendra | June 23, 2020 Jubilant Therapeutics Inc., a biopharmaceutical organization propelling little particle modulators to address neglected clinical needs in oncology and immune system infections, today declared that preclinical information of double LSD1 and HDAC6 inhibitor JBI-802, will be introduced in a banner meeting at the American Association for Cancer Research (AACR) 2020 Virtual Annual Meeting II. The preclinical …
New technology May Raise the quality of stem cells Found in regenerative medicine Kumar Jeetendra | July 8, 2020 Stem cells have been holding great promise for regenerative medicine for ages. In the last decade, many studies have revealed this form of cell, which in Spanish is called”mother cell” due to its ability to contribute to various different cell types, may be applied in regenerative medicine to diseases such as muscle and nervous system …
Study reveals new insight into neurobiological procedures that control medicate related adjustments Kumar Jeetendra | July 10, 2020 This molecular atlas is”a previously unachieved degree of cellular resolution for cocaine-mediated receptor regulation in this area,” said Day, an associate professor in the UAB Department of Neurobiology. The atlas was only the launch of a significant study, published in the journal Science Advances, which utilized multiple cutting-edge technologies to spell out a more dopamine-induced …
Study uncovers antiviral impacts of curcumin Kumar Jeetendra | July 19, 2020 Curcumin, a natural compound found in the spice turmeric, could help remove specific viruses, studies have found. A study published in the Journal of General Virology revealed that curcumin can prevent Transmissible gastroenteritis virus (TGEV) – an alpha-group coronavirus that infects pigs – from infecting cells. At higher doses, the compound was also found to …
SUTD researchers utilize 3D printing to make heart cells from undifferentiated organisms Kumar Jeetendra | August 12, 2020 All people start out from one cell that then divides to eventually form the embryo. Based on the signals sent with their own adjacent cells, these divided cells are then developed or differentiated into particular organs or tissues. In regenerative medicine, controlling this differentiation from the lab is crucial as stem cells could be distinguished …
Biocompatible photooxygenation catalyst could be conceivably used to treat amyloid infections Kumar Jeetendra | November 26, 2020 The catalyst was able to oxygenate Aβ embedded beneath the skin of a living mouse, and diminished intact Aβ degree in AD-model mouse brain. The new catalyst is potentially useful for the treatment of peripheral amyloid diseases and AD. Toxic aggregation of amyloid peptide and protein is closely associated with a number of human diseases. …
New consortium aims to comprehend principles underlying the formation of coronaviruses Kumar Jeetendra | December 10, 2020 “This consortium will aim to comprehend the physical principles underlying the formation of coronaviruses,” said Roya Zandi, a professor of physics and astronomy at UC Riverside and the principal investigator of this four-year project that received funding of over $1.75 million. “We will also explore the effect of some drugs on the assembly process.” Zandi …
Scientists plan new biosynthetic pathways for short-chain essential amines Kumar Jeetendra | January 18, 2021 Researchers report a new strategy for the microbial production of multiple short-chain primary amines through retrobiosynthesis. KAIST metabolic engineers introduced the bio-based production of numerous short-chain primary amines that have a broad assortment of applications in chemical industries for the first time. The research team led by Distinguished Professor Sang Yup Lee from the Department …
Inflammation may add to the determination of C. diff disease, shows study Kumar Jeetendra | January 19, 2021 A new study from North Carolina State University indicates that the inflammation brought on by Clostridioides difficile (C. diff) infection gives the pathogen a two-fold advantage: by both creating an inhospitable environment for competing bacteria and supplying nutrients that enable C. diff to thrive. C. diff is a bacterium that causes diarrhea, often with severe …
Pancreatic β cell-inferred exosomal miR-29s control glucose homeostasis Kumar Jeetendra | January 24, 2021 In a new study published in Journal of Extracellular Vesicles, Chen-Yu Zhang’s team at Nanjing University, School of Life Sciences, and Antonio Vidal-Puig’s group at University of Cambridge report that pancreatic β cells secrete miR-29 family members (miR-29s) via exosomes in reaction to high levels of free fatty acids (FFAs). Formerly, Chen-Yu Zhang’s team identified …
UNSW builds up a clay based ink to 3D-print bone parts with living cells Kumar Jeetendra | January 26, 2021 3D printers may one day become a permanent fixture of the operating theatre after UNSW scientists showed they could print bone-like structures comprising living cells. Researchers from UNSW Sydney have developed a ceramic-based ink which may allow surgeons in the long run to 3D-print bone elements complete with living cells which could be used to …
CN Bio presents the PhysioMimix™ OOC Multi-Organ Microphysiological System Kumar Jeetendra | March 17, 2021 CN Bio, a leading developer of single and multi-organ microphysiological systems (MPS), otherwise known as organ-on-a-chip (OOC), today announced the commercial launch of its new PhysioMimix™ OOC Multi-Organ MPS. The next-generation system unites CN Bio’s in vitro 3D liver model, whose phenotype and functions mimic that in vivo, with a range of other organs to …
