Asthma doesn’t seem to expand the danger of contracting COVID-19, shows study Kumar Jeetendra | July 6, 2020 Asthma doesn’t seem to increase the risk for an individual contracting COVID-19 or influence its own seriousness, as shown by a group of Rutgers research workers. “However, individuals with allergies –even those with diminished lung function that are being treated to control asthmatic inflammation–appear like no worse influenced by SARS-CoV-2 compared to the usual non-asthmatic …
Study shows how mast cells manage calcium levels to control the invulnerable reaction Kumar Jeetendra | July 23, 2020 Instead of protecting us, the immune system can sometimes go awry, as in the case of autoimmune disorders and allergies. An Ludwig-Maximilian-Universitaet (LMU) in Munich group has dissected how mast cells modulate their calcium levels to maintain the immune response under control. The immune system defends us against attack by germs and viruses and also …
Test mRNA-based COVID-19 immunization evokes defensive safe reactions in animals Kumar Jeetendra | July 25, 2020 Two injections of this vaccine were enough to induce robust immunity, completely preventing SARS-CoV-2 infection in mice. MRNA-based vaccines are all attractive options for protecting against SARS-CoV-2 because they may be quickly designed and manufactured at a huge scale within weeks. Moreover, preclinical studies have shown that mRNA-based vaccines cause potent and broadly protective immune …
Protein delivered by the human safe framework can emphatically hinder Sars-Cov-2 Kumar Jeetendra | August 3, 2020 A protein produced by the human immune system may strongly inhibit corona viruses, including Sars-Cov-2, the pathogen causing Covid-19. An international team from Germany, Switzerland and the USA successfully showed the LY6E-Protein prevents coronaviruses from causing the illness. “This finding may result in the development of new therapeutic approaches against coronaviruses,” says Professor Stephanie Pfänder …
Propelled investigation offers new experiences into safe framework’s job in serious COVID-19 Kumar Jeetendra | August 14, 2020 By conducting complex diagnoses of immune system stimulation in patients with acute COVID-19, researchers at Karolinska Institutet have managed to spot several cell types that play a key part in the immune reaction to the new coronavirus and the hyperinflammation found in severe cases of the disease. The results are published in the scientific journal …
Examination shows how a protein prevents cells from assaulting their own DNA Kumar Jeetendra | August 20, 2020 Viruses multiply by injecting their DNA into a host cell. Once it passes the intracellular fluid, then this foreign substance triggers a defense mechanism referred to as the cGAS-STING pathway. This, in turn, binds to another protein named Stimulator of Interferon Genes (STING), which induces an inflammatory immune reaction. From time to time, the material …
CRISPR-based framework smothers qualities identified with AAV antibody production Kumar Jeetendra | September 9, 2020 Gene therapy generally is based on viruses, such as adeno-associated virus (AAV), to deliver genes into a cell. In the event of CRISPR-based gene therapies, molecular scissors can then snip out a faulty gene, add in a missing arrangement or enact a temporary change in its expression, but the body’s immune response to AAV can …
Study surveys ongoing bits of knowledge into the pathogenesis of feline leukemia virus contamination Kumar Jeetendra | September 10, 2020 Feline leukemia virus (FeLV) is a gammaretrovirus that occurs worldwide in domestic cats, in addition to small wild cats. It’s associated with various severe, and sometimes fatal, diseases including anaemia, immunosuppression and certain cancers. First described over 55 years ago, FeLV has been the topic of intense research interest, which has led to increasingly robust …
New T-cell-based immunization procedure gives more extensive insurance against occasional flu Kumar Jeetendra | September 24, 2020 As Americans begin pulling their sleeves up for an annual flu vaccine, researchers at the University of Wisconsin-Madison have provided new insights into an alternate vaccine approach that provides wider protection against seasonal flu. In a study published in Cell Reports Medicine today (Sept. 22), scientists describe a T-cell-based vaccine strategy that’s effective against multiple …
Scientists study misleading impact in nausea therapy at the molecular level Kumar Jeetendra | September 28, 2020 The molecular bases of the placebo effect are poorly understood. A team headed by Ludwig-Maximilians-Universitaet (LMU) in Munich researcher Karin Meissner has now studied the phenomenon in the context of nausea, and identified specific proteins that correlate with its positive impact. The placebo effect seems to work wonders. In certain cases, administration of a’drug’ to …
PC model disentangles puzzle behind serious aggravation in individuals with COVID-19 Kumar Jeetendra | September 29, 2020 A study from the University of Pittsburgh School of Medicine and Cedars-Sinai addresses a mystery first raised in March: Why do some people with COVID-19 develop severe inflammation? The research shows how the molecular arrangement and arrangement of the SARS-CoV-2 spike protein–part of the virus that causes COVID-19–could be behind the inflammatory syndrome cropping up …
Amniotic liquid undifferentiated cells may prompt better treatment for ischemic stroke Kumar Jeetendra | October 7, 2020 A study published today in STEM CELLS Translational Medicine points the way to a potential new avenue of treatment for ischemic stroke. The study, led by Annamaria Cimini, Ph.D., of the University of L’Aquila, and Liborio Stuppia, M.D., of D’Annunzio University, Italy, shows how the secretome of amniotic fluid stem cells can restore neuronal plasticity …
