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    hot-stage microscopy (HSM)

    Hot stage optical microscopy as an analytical tool to understand solid state changes in particle Characterization

    When drug crystals are heated they undergo changes that can be observed under a microscope. Characteristics that can be analyzed under a microscope include melting point, melting range, crystal nucleation, crystal growth, crystal transformations and more. For example, under a microscope it is easy to see when a solid melts or how crystals nucleate and