Study affirms most basic complexities related with COVID-19

Study affirms most basic complexities related with COVID-19


  • Post By : Kumar Jeetendra

  • Source: Canadian Medical Association Journal

  • Date: 08 Dec,2020

A large study of patients in america who contracted coronavirus disease 2019 (COVID-19) confirms many complications of the disease, according to new research in CMAJ (Canadian Medical Association Journal).

Understanding the full range of associated conditions can aid in prognosis, guide treatment decisions and better inform patients as to their actual risks for the variety of COVID-19 complications reported in the literature and media.”

Dr. William Murk, Jacobs School of Medicine & Biological Sciences, University at Buffalo, Buffalo, New York, Coauthors, Aetion, Inc., HealthVerity, Inc., University of Toronto

Using de-identified outpatient and inpatient medical claims from a United States health database, researchers identified 70 288 patients who had a COVID-19-related health visit between March 1 and April 30, 2020. Over half of all patients were admitted to hospital, and approximately 5% were admitted to the intensive care unit. The median age was 65 years, and 55.8% were female.

The absolute risk of someone with COVID-19 having these severe conditions was 27.6% for pneumonia, 22.6% for respiratory failure, 11.8percent for kidney failure and 10.4percent for sepsis or systemic inflammation.

The researchers also found relationships with a range of other lung and cardiovascular conditions, such as diminished lung, blood clotting disorders and heart inflammation, even though the risk of these was comparatively low. Contrary to results of other research, COVID-19 did not seem to be associated with a greater risk of stroke.

“This analysis provides estimates of absolute risk and relative odds for all identified diagnoses associated with COVID-19, which are required to help patients, providers and policy-makers understand the chance of complications,” write the authors.

Journal reference:

Murk, W., et al. (2020) Diagnosis-wide analysis of COVID-19 complications: an exposure-crossover study. Canadian Medical Association Journal.

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