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Dear Readers,Welcome to the latest issue of Microb
Asthma is an allergic disorder characterized by difficulty breathing, chest pain, and cough and wheezing and disease is commonly managed by inhalers.
According to World Health Organization as of 2011, 235–330 million people worldwide are affected by asthma, and approximately 250,000–345,000 people die per year from the disease. Now researcher from Penn State Milton S. Hershey Medical Center uncover a mystery over asthma and successful in detection of compound named “telltale molecules” circulating through out body and now this researcher play an important in first time in pathology history as detection of asthma through blood test.
"Right now, we diagnose asthma based on someone's history and breathing tests — and both of those have limitations," said Dr. Faoud T. Ishmael, associate professor of medicine and biochemistry and molecular biology.
According to detailed report, Some asthma patients do not find relief from inhaled corticosteroids, the mainstay of asthma treatment. Asthma sub-types could play a role in this but "there's not a good way right now to understand what those different sub-types are," Ishmael said. "This goes back to the underlying issue, which is that we don't have a good blood test to tell us what's really going on in the lungs."
This interesting research recently appears in The Journal of Allergy and Clinical Immunology.
"Our goal is to have a blood test for asthma developed in the next five years," Ishmael said. "You might be able to take a drop of blood from a finger stick and analyze it in the clinic to determine whether someone has asthma at that visit. That would be the ultimate goal."
Note: The above story is for information purposes for more information go through original story source.
Story source:Penn State Milton S. Hershey Medical Center
Journal references:Ronaldo P. Panganiban, Yanli Wang, Judie Howrylak, Vernon M. Chinchilli, Timothy J. Craig, Avery August, Faoud T. Ishmael. Circulating microRNAs as biomarkers in patients with allergic rhinitis and asthma. Journal of Allergy and Clinical Immunology, 2016; DOI: 10.1016/j.jaci.2016.01.029
