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In the mitochondria of eukaryotic cells is a metabolic mechanism known as the Krebs Cycle, which is also known as the TCA cycle or citric acid cycle.
Within the mitochondria of eukaryotic cells is where the Krebs cycle occurs in its majority, in the matrix of mitochondria. Because they generate energy via Kreb’s cycles and oxidative phosphorylation, these organelles are called mitochondria. The Structure of
In addition to their outer membrane, mitochondria also have an inner membrane that encases the matrix within.
As an example, ATP is produced through a series of enzymatic events using acetyl-CoA, which is produced by several metabolic pathways such as beta-oxidation and glycolysis. NADH and FADH2 are then utilized as reducing equivalents and electron carriers, respectively. Coenzyme A (CoA) connected to an acetyl group undergoes a sequence of conversions to citrate in these reactions, which in turn release carbon dioxide and produce reducing equivalents and precursors for ATP synthesis.
In summary, Krebs cycle is a fundamental process of cellular respiration that oxidizes acetyl-CoA from various metabolic pathways generating ATP and reducing equivalents; thus it happens within mitochondria matrix. In these eukaryotic cells, this cyclic pathway is important to generate energy and maintain cell function.