CN Bio presents the PhysioMimix™ OOC Multi-Organ Microphysiological System Kumar Jeetendra | March 17, 2021 CN Bio, a leading developer of single and multi-organ microphysiological systems (MPS), otherwise known as organ-on-a-chip (OOC), today announced the commercial launch of its new PhysioMimix™ OOC Multi-Organ MPS. The next-generation system unites CN Bio’s in vitro 3D liver model, whose phenotype and functions mimic that in vivo, with a range of other organs to …
INTEGRA’s electronic pipettes empower reproducible examination in microbial analysis Kumar Jeetendra | March 17, 2021 Bacterial evolution studies involve analysis of large sample numbers, requiring compact, reproducible pipetting processes to effectively characterize the qualities of different strains. Dr Astrid Altamirano-Junqueira, who completed her doctoral studies into the growth of bacterial motility in the School of Biological Studies at Reading University, discussed how these digital pipettes aided her research:”My focus was …
Study uncovers immune defense system that shields the lungs from viral diseases Kumar Jeetendra | March 18, 2021 Scientists have discovered a previously unknown arm of the immune defense system that protects the lung from lethal viral infections. Respiratory diseases caused by viruses such as influenza A and SARS-CoV-2 cause harm not only through their own activities, but also from collateral damage as the immune system reacts to combat the infection. A timely …
Study shows how self-swimming microorganisms get by in harsher conditions Kumar Jeetendra | March 18, 2021 Many bacteria swim towards nutrients by rotating the helix-shaped flagella attached to their bodies. As they proceed, the cells may either’run’ in a straight line, or’fall’ by varying the rotational directions of the flagella, inducing their avenues to intentionally alter course. Through a process named’chemotaxis,’ bacteria can decrease their rate of tumbling at higher levels …
Scientists portray regions of DNA that sway MECP2 expression Kumar Jeetendra | March 19, 2021 Researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital (NRI) have identified and characterized two regions of DNA required for the proper expression of Mecp2/MECP2 in mice and humans. These findings, published in Genes & Development, are helping to shed light on the purpose of …
Secret genetic defects can prompt a wide range of serious illnesses Kumar Jeetendra | March 20, 2021 For the first time researchers from Hebrew University of Jerusalem, Radboudumc, Maastricht UMC+ and worldwide colleagues have gained insight to the”hidden genetic defects” of the general European population. This is important as these defects, if inherited from the father and mother, can result in all kinds of disorders in their children. Research in the Dutch …
Intense openness of lung tissue to vape airborne lesserly affects gene expressionthan cigarette smoke Kumar Jeetendra | March 21, 2021 A new peer-reviewed study published in the journal Toxicological Research & Application reveals acute exposure of a 3D human bronchial tissue model to e-cigarette aerosol has minimal impact on gene expression in contrast to smoke from combustible cigarettes. The study included sub-cytotoxic vulnerability to cells in a 3D human bronchial model (MucilAirTM) to nicotine-containing vape …
Study maps design and system of a membrane enzyme that assumes part in inflammation, cancer Kumar Jeetendra | March 21, 2021 Most drugs operate via the membranes that surround the body’s cells. The analysis, which is printed in the journal Nature Communications, can make a significant contribution to the development of potential drugs. The cells’ equal to organs, the organelles, are enclosed by membranes. Embedded in the cell’s external and internal membranes are proteins that regulate …
Bacteria residing within inside tumor cells can support malignant growth immunotherapy Kumar Jeetendra | March 22, 2021 Cancer immunotherapy may get a boost from an unexpected direction: bacteria residing within tumor cells. The study may also help clarify the connection between immunotherapy and the intestine microbiome, describing the findings of earlier research that the microbiome impacts the success of immunotherapy. Immunotherapy remedies of the last decade or so have dramatically improved healing …
Researcher find a gene mutation connected to schizophrenia Kumar Jeetendra | March 24, 2021 Researchers at The Feinstein Institutes for Medical Research, in collaboration with Columbia University, have identified a gene mutation that could result in schizophrenia, a chronic brain disease that affects nearly 1 percent of the planet’s inhabitants. The findings, published in today in Neuron, could lead to novel treatment strategies. The research group, headed by Todd …
Researchers discover proof that SARS-CoV-2 infects cells in the mouth Kumar Jeetendra | March 25, 2021 An international group of scientists has discovered evidence that SARS-CoV-2, the virus that causes COVID-19, infects cells in the mouth. While it’s well known that the upper airways and lungs are primary sites of SARS-CoV-2 disease, there are clues the virus can infect cells in different parts of the body, like the digestive system, blood …
Researchers describe the systems that manage embryonic stem cells Kumar Jeetendra | March 26, 2021 Scientists at the Proteomics Core Unit of the Spanish National Cancer Research Centre (CNIO), headed by Javier Muñoz, have clarified the mechanisms, unknown to date, included in maintaining embryonic stem cells in the best possible condition for their use in regenerative medicine. The results, published in Nature Communications, helps to find novel stem-cell therapies for …
