Scientists recognize neural circuit associated with reciprocally controlling weight gain and despondency Kumar Jeetendra | March 27, 2021 Research has found that obesity and mental disorders such as depression and anxiety seem to often go together. Researchers at Baylor College of Medicine and cooperating institutions are providing new insights into this association by identifying and characterizing a novel neural circuit that mediates the reciprocal control of feeding and mental conditions in mouse models. …
Study uncovers molecular mechanisms of drug resistance in Mycobacterium tuberculosis Kumar Jeetendra | April 9, 2021 A consortium of researchers from Russia, Belarus, Japan, Germany and France led by a Skoltech scientist have uncovered the way by which Mycobacterium tuberculosis survives in iron-deficient states by using rubredoxin B, a protein by a rubredoxin family that play an essential role in adaptation to changing environmental conditions. The new study is part of …
Scientists use genetics to recognize likely drugs for early administration of COVID-19 Kumar Jeetendra | April 12, 2021 A new study using human genetics indicates researchers should prioritize clinical trials of drugs that target two proteins to manage COVID-19 in its early stages. The findings appeared online in the journal Nature Medicine at March 2021. The purpose is to identify present drugs, either FDA-approved or in clinical development for other conditions, that can …
Small SARS-CoV-2 protein may have huge ramifications for future COVID-19 medicines Kumar Jeetendra | April 12, 2021 A very small protein of SARS-CoV-2, the coronavirus that gives rise to COVID-19, may have big implications for future therapies, according to a team of Penn State researchers. Using a novel toolkit of approaches, the scientists uncovered the first full structure of the Nucleocapsid (N) protein and discovered how antibodies from COVID-19 patients interact with …
Imbalanced bacterial community in the gums connected to Alzheimer’s infection biomarker Kumar Jeetendra | April 12, 2021 Older adults with more harmful than healthy bacteria in their gums are more likely to have evidence for amyloid beta–a key biomarker for Alzheimer’s disease–in their cerebrospinal fluid (CSF), according to new research from NYU College of Dentistry and Weill Cornell Medicine. However, this imbalance in oral bacteria was not associated with another Alzheimer’s biomarker …
Study offers a non-obtrusive avenue for monitoring buildings for COVID-19 Kumar Jeetendra | April 14, 2021 A study done in rooms where COVID-19 patients were isolated reveals that the virus’s RNA – part of the genetic material inside a virus – can persist up to a month in dust. The study did not evaluate whether dust may transmit the virus to people. It could, however, offer another option for monitoring COVID-19 …
Pregnancy builds the danger of first-time symptomatic kidney stone Kumar Jeetendra | April 15, 2021 Though researchers have long known that several physiological and anatomical changes occur during pregnancy which could contribute to kidney stone formation, evidence of the connection has been lacking. An observational study that reviewed the medical records for nearly 3,000 female patients from 1984 to 2012 finds that pregnancy increases the risk of a first-time symptomatic …
Three-sided molded spikes help the success of Covid transmission Kumar Jeetendra | April 16, 2021 COVID-19 requires no introduction. This past year, the disease, which is caused by the virus SARS-CoV-2, reached every continent across the globe. From the end of March 2021, there had been an estimated 128 million cases listed with nearly three million of these being deadly. As scientists’ race to produce vaccines and politicians coordinate their …
Genetic variants that sway protein restricting in immune cells can cause autoimmune disease Kumar Jeetendra | April 17, 2021 Certain genetic variants that cause modified protein binding in immune cells, are also seen in people at high risk of some autoimmune diseases, new research has found. Researchers from the Wellcome Sanger Institute, Josep Carreras Leukaemia Research Institute in Spain, and the MRC London Institute of Medical Sciences (LMS) discovered that specific genetic variants, which …
Researchers enlighten how a few antibodies can viably disable ebolaviruses Kumar Jeetendra | April 18, 2021 Some survivors of ebolavirus outbreaks create antibodies that may broadly neutralize those viruses–and today , scientists at Scripps Research have illuminated how these antibodies can disable the viruses so efficiently. The insights might be helpful for developing effective treatments. Ebolavirus is a family of often-deadly viruses that includes Ebola virus and lots of lesser-known viruses …
FDA denies EUA for monoclonal antibody treatment bamlanivimab to treat patients with COVID Kumar Jeetendra | April 18, 2021 Now, the U.S. Food and Drug Administration revoked the emergency use authorization (EUA) that allowed for the investigational monoclonal antibody treatment bamlanivimab, when administered alone, to be utilized for treating mild-to-moderate COVID-19 in adults and certain pediatric patients. Based on its ongoing analysis of emerging scientific data, specifically the sustained increase of SARS-CoV-2 viral variants …
New examination reveals insight into complex brain measure that learns and structure new memories Kumar Jeetendra | April 19, 2021 Making memories involves over seeing friends or taking photos. How neurons do so –reaching out arm-like dendrites to communicate with other neurons–requires a ballet of genes, signaling molecules, cellular scaffolding and protein-building machinery. A new study from scientists at Scripps Research and the Max Planck Florida Institute for Neuroscience finds a fundamental role for one …
