First enzyme driven biocatalytic creation of nucleic acid structure blocks Kumar Jeetendra | December 15, 2020 Researchers in TU Graz and acib succeed in the first enzyme-driven biocatalytic synthesis of lipoic acid building blocks. This facilitates the development of antiviral agents and RNA-based therapeutics. Because of this COVID 19 pandemic and the related intensive search for therapeutics and vaccines, the chemical substance class of nucleosides is undergoing an enormous increase in …
New information shows empowering results for patients with neuro-degenerative blinding eye illness Kumar Jeetendra | December 16, 2020 New data published in the Journal Science Translational Medicine shows encouraging results in a worldwide clinical trial for patients diagnosed with the neuro-degenerative blinding eye disease; Leber Hereditary Optic Neuropathy (LHON. The disease is an inherited type of vision loss estimated to affect 1 in 30,000 to 50,000 individuals. LHON most often afflicts individuals with …
Another way to deal with distinguish genomic areas in our cerebrum that add to make us human Kumar Jeetendra | December 17, 2020 With just 1% gap, the human and chimpanzee protein-coding genomes are remarkably similar. Knowing the biological characteristics that make us human is a part of a fascinating and intensely debated line of study. The paper is printed in Science Advances. Gene expression, not gene arrangement To describe what sets human besides their ape relatives, researchers …
Pig stem cells offer another approach to develop human organs for transplantation Kumar Jeetendra | December 18, 2020 In a new paper published in Stem Cell Reports, Bhanu Telugu and co-inventor Chi-Hun Park of the University of Maryland (UMD) Department of Animal and Avian Sciences show for the first time that newly generated stem cells from cows, when injected into embryos, contributed to the growth of only the organ of interest (the embryonic …
new cGMP plasmid DNA manufacturing facility construction announced by Thermo Fisher Kumar Jeetendra | December 18, 2020 Thermo Fisher Scientific, the world leader in serving science, today announced the construction of a new cGMP plasmid DNA manufacturing facility in Carlsbad, Calif. The site will expand the company’s clinical and commercial capabilities for cGMP plasmid DNA used as a critical raw material to develop and manufacture cell and gene-based therapies including life-saving cancer …
Study recognizes biomarker gene mark that demonstrates likely liver toxicity Kumar Jeetendra | December 19, 2020 When agrochemical and pharmaceutical companies develop new products, they must test extensively for potential toxicity before obtaining regulatory approval. This testing usually involves lengthy and expensive animal research. A research team at University of Illinois has developed a gene biomarker identification technique that cuts the testing process down to a couple of days while still …
Scientists found and describe two contagious species unexpectedly Kumar Jeetendra | December 20, 2020 University of Copenhagen scientists have found and described two fungal species for the first time. The fungi infect adult flies and then create a hole in the gut of the hosts’ bodies. Infected flies then buzz around days as the fungi devour them from within and eject fungal spores from these holes in their bodies. …
Hematoxylin compounds can specifically kill CALR freak disease cells Kumar Jeetendra | December 20, 2020 Patients with myeloproliferative neoplasm (MPN), a group of malignant diseases of the bone marrow, often have a carcinogenic mutated form of the calreticulin gene (CALR). Scientists of the research group of Robert Kralovics, Adjunct Principal Investigator in the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences and team leader at the …
Digital chest drainage systems could help reduce COVID-19 spread, research show Kumar Jeetendra | December 20, 2020 Pioneering research, which reveals digital chest drains generate and disperse less aerosol generated particles in comparison to traditional water seal systems, has been published in the Seminars in Thoracic and Cardiovascular Surgery journal. The research was led by a group of thoracic consultants from Guy’s and St Thomas’ NHS Foundation Trust — home to one …
New comprehension of physical properties of chromatin may show how genome is encoded and decoded Kumar Jeetendra | December 21, 2020 University of Alberta researchers have found an answer to a basic question in genomic biology that has eluded scientists because the discovery of DNA: Over the nucleus of our cells, is the complex package of DNA and proteins called chromatin a solid or a liquid? Previously, fields like biochemistry operated under the premise that chromatin …
Trinity crew uncovers mutations connected with early onset dementia Kumar Jeetendra | December 22, 2020 Researchers at Trinity College Dublin today announced a significant advance in our knowledge of an early onset form of dementia which may also advance our understanding of conditions such as Alzheimer’s disease. Adult onset Leukoencephalopathy with axonal Spheroids and Pigmented glia (ALSP) is an ultra-rare condition characterized by mutations in a gene named Colony stimulating …
New drug mixture improves blood glucose manipulate and weight reduction in mice Kumar Jeetendra | December 23, 2020 Scientists have demonstrated that adding an experimental cancer drug to a widely used diabetes treatment improves blood glucose control and weight loss in mice, according to a study published today in eLife. The results pave the way for clinical trials of this new drug combination as a more successful long-term remedy for countless individuals with …
