A short-reduce in photosynthetic equipment can permit needles of pine bushes to live green Kumar Jeetendra | December 24, 2020 How do conifers which are used for example as Christmas trees keep their green needles over the boreal winter when many trees drop their leaves? Science hasn’t provided a good response to this question but now an international group of scientists, including researchers in Umeå University, has deciphered that a short-cut in the photosynthetic machinery …
Researchers pick out new weapon to war the growing tide of antibiotic-resistant bacteria Kumar Jeetendra | December 24, 2020 As scientists around the globe wage war against a publication, deadly virus, one University of Colorado Boulder laboratory is working on new weapons to battle a distinct microbial threat: a rising tide of antibiotic-resistant bacteria which, if left unattended, could kill an estimated 10 million people annually by 2050. In a paper published Friday in …
Study clarifies the impact of getting old on hematopoietic stem cells Kumar Jeetendra | December 25, 2020 By shifting mouse elderly hematopoietic stem cells (aged HSCs) to the environment of young mice (bone marrow niche), it was shown that the pattern of stem cell gene expression was rejuvenated to that of young hematopoietic stem cells. On the other hand, the function of elderly HSCs failed to recover in the young bone marrow …
Polygenic threat ratings from multi-populace information should enhance IBD predictions Kumar Jeetendra | December 25, 2020 Using genetic data from nearly 30,000 individuals, Mount Sinai researchers have assembled hazard scores from a combination of datasets representing distinct ancestral populations that improve prediction of risk for inflammatory bowel diseases (IBD) including Crohn’s disease and ulcerative colitis. The research was published in Gastroenterology on December 24. The researchers found that polygenic risk scores, …
Study famous how ecDNA fragments pressure gene amplification to generate drug resistance in cancer Kumar Jeetendra | December 26, 2020 Researchers headed by Ludwig San Diego Member Don Cleveland and Peter Campbell of the Sanger Center have solved the puzzle of how free-floating circular DNA fragments, which are almost exclusively found in cancer cells, drive gene amplification to create drug resistance in cancer. The study, published on December 23 in the journal Nature, provides new …
Researchers locate mechanism underlying plasticity in grownup brains Kumar Jeetendra | December 27, 2020 Developing brains continuously sprout new neuronal connections called synapses as they understand and remember. Important connections — the ones that are repeatedly introduced, such as how to avoid danger — are nurtured and reinforced, while links deemed unnecessary are pruned away. Adult brains experience similar pruning, but it was unclear why or how synapses in …
Researchers find out how shattered chromosomes make most cancers cells greater aggressive Kumar Jeetendra | December 27, 2020 Cancer is one of the world’s biggest health afflictions because, unlike some diseases, it’s a moving target, constantly evolving to evade and resist treatment. In a paper published in the December 23, 2020 online dilemma of Nature, researchers at University of California San Diego School of Medicine and the UC San Diego branch of the …
Surgery may expand length of endurance for metastatic breast malignant growth patients Kumar Jeetendra | December 28, 2020 They studied nearly 13,000 stage four breast cancer patients and found that those who had surgery as well as their other remedies had a survival advantage over those who had other therapies alone. Stage four breast cancer accounts for 6% of newly-diagnosed breast cancer cases. Systemic treatment, which may include treatments like chemotherapy, hormone therapies …
FDA favors first conventional glucagon for injection to treat extreme hypoglycemia Kumar Jeetendra | December 29, 2020 Today, the U.S. Food and Drug Administration approved the first generic of glucagon for injection USP, 1 mg/vial packed in an emergency kit, for the treatment of severe hypoglycemia (very low blood sugar), which may occur in patients with diabetes mellitus. The drug is also indicated as a diagnostic aid in the radiologic examination of …
Poisonous pesticide transformed into treatment against antibiotic-resistant bacteria Kumar Jeetendra | December 30, 2020 They are used as pesticides and fungicides. However, these substances could be poisonous to humans and cause mutations. As they aren’t frequently used, there’s little data about them in the medicinal chemistry literature. However, it has been suggested recently that the groups of substances that are traditionally avoided can help to fight pathogenic bacteria. Yet, …
Older adults, minorities and individuals with lower salaries face disparities in telemedicine use Kumar Jeetendra | December 31, 2020 After”COVID-19,” the word which most people will remember best from 2020 is very likely to be”social distancing.” While it most commonly applied to social gatherings with family and friends, it has changed how many receive medical attention. However, the COVID-19 pandemic, particularly in the spring of 2020, required increased use of virtual or telephone call …
Sustainable immune dysregulation because of COVID-19 in non-hospitalized patients Kumar Jeetendra | December 31, 2020 COVID-19, which has killed 1.7 million people globally, doesn’t follow a uniform path. Others, especially those with comorbidities, can create severe clinical disease with atypical pneumonia and multiple system organ failure. Since the first cases were reported in December 2019, the SARS-CoV-2 virus that causes COVID-19 has surged into a pandemic, with cases and deaths …
