New UCLA-formed gadget moves mitochondria into at least 100,000 or more beneficiary cells Kumar Jeetendra | January 1, 2021 Scientists from the UCLA Jonsson Comprehensive Cancer Center have developed a simple, high-throughput way of transferring isolated mitochondria and their associated mitochondrial DNA into mammalian cells. This approach enables researchers to tailor a key genetic component of cells, to study and potentially treat debilitating diseases such as cancer, diabetes and metabolic disorders. A study, published …
Smoking traditional cigarettes alongside e-cigarettes causes harmful wellbeing impacts Kumar Jeetendra | January 4, 2021 Smoking traditional cigarettes in addition to using e-cigarettes leads to harmful health effects like smoking cigarettes exclusively, according to new research published today in the American Heart Association’s flagship journal Circulation. Smoking, a well-known link to cardiovascular disease and death, seems to be on the decline. While using e-cigarettes, known as vaping, is increasingly popular, …
FDA-endorsed COVID-19 medication should be utilized warily, says UC researcher Kumar Jeetendra | January 4, 2021 While the world has its eyes on vaccines to stop the spread of coronavirus, therapeutics continue to be necessary to treat hepatitis patients. One of these treatments, remdesivir, is the first and only antiviral agent of its type the U.S. Food and Drug Administration (FDA) has approved so far for COVID-19. Research at the University …
Scientists disentangle the cycle that makes virus irresistible Kumar Jeetendra | January 9, 2021 Researchers have for the first time identified how viruses like the poliovirus and the common cold virus’package up’ their genetic code, allowing them to infect cells. The findings, published today (Friday, 8 January) in the journal PLOS Pathogens by a team from the Universities of Leeds and York, open up the possibility that medication or …
Gene therapy can viably treat mice with tuberous sclerosis complex, shows study Kumar Jeetendra | January 9, 2021 Patients with tuberous sclerosis complex, a genetic disorder characterized by the growth of noncancerous tumors in several organs of the body, have limited treatment choices. A team led by investigators at Massachusetts General Hospital (MGH) has shown that gene therapy can effectively treat mice that express one of the mutated genes that cause the disease. …
Biomarkers can foresee how hereditarily identical cells act distinctively under pressure Kumar Jeetendra | January 10, 2021 A set of biomarkers not traditionally associated with cell fate can accurately forecast how genetically identical cells behave differently under pressure, according to a UT Southwestern study. The findings, published by Cell Reports as a Dec. 1 cover story, could eventually result in more predictable responses to pharmaceutical remedies. Groups of the same types of …
Researchers arrive at significant achievement in leishmaniasis immunization advancement Kumar Jeetendra | January 11, 2021 Scientists have taken an important step forward in creating a controlled human infection model to test leishmaniasis vaccines. The University of York-led study identified and characterized a new strain of Leishmania parasite that will form the basis of a new controlled human infection model for the disease which is transmitted by the bite of sand …
Scientists gives better comprehension of how antibiotic resistance emerges Kumar Jeetendra | January 11, 2021 Researchers at the Quadram Institute on the Norwich Research Park have shown how the development of antibiotic resistance by bacteria may have’side-effects’ for them including affecting their ability to induce disease. Antibiotic resistance is still one of the best challenges to global health with very few new antibiotics and widespread immunity. It’s been estimated that …
Boosting a characteristic cell cycle could bring down ventilator-related lung damage Kumar Jeetendra | January 12, 2021 An unfortunate truth about the use of mechanical ventilation to save the lives of patients in respiratory distress is that the pressure used to inflate the lungs is very likely to cause further lung damage. In a new study, scientists identified a molecule that’s produced by immune cells during mechanical ventilation to try to decrease …
Study shows distancing and mandatory masks can forestall 87% of grounds COVID-19 diseases Kumar Jeetendra | January 13, 2021 The combined effectiveness of three COVID-prevention strategies on college campuses–mask-wearing, social distancing, and routine testing–are equally as effective in preventing coronavirus infections as the Pfizer and Moderna vaccines approved by the U.S. Food and Drug Administration (FDA), according to a new study co-authored by a Case Western Reserve University researcher. The study, published in Annals …
Analysts recognize interface among ALS and collection of DNA-RNA hybrids in the genome Kumar Jeetendra | January 13, 2021 Researchers from the University of Seville and the University of Pavia have identified a connection between Amyotrophic Lateral Sclerosis (ALS) and the accumulation of DNA-RNA hybrids in the genome. The accumulation of these hybrids causes increased genomic damage and boosts genetic instability. This finding will make it possible to better understand the molecular basis of …
The Cancer Microbiome Atlas gives more clear picture of microbiota living in organs Kumar Jeetendra | January 14, 2021 Biomedical engineers at Duke University have devised an algorithm to remove contaminated microbial genetic information from The Cancer Genome Atlas (TCGA). With a clearer picture of the microbiota living in a variety of organs in both healthy and cancerous states, researchers will now have the ability to find new biomarkers of disease and better understand …
