Genomic surveillance can help recognize how SARS-CoV-2 spreads in care homes Kumar Jeetendra | March 4, 2021 Care homes are at high risk of experiencing outbreaks of COVID-19, the disease brought on by SARS-CoV-2. Older people and people affected by heart disease, respiratory disease and type 2 diabetes – all of which increase with age – are at greatest risk of severe disease and even death, which makes the care home population …
Diphtheria is developing to get antibiotic-resistant safe and could prompt vaccine escape Kumar Jeetendra | March 8, 2021 Diphtheria – a comparatively easily-preventable infection – is evolving to become immune to a range of types of antibiotics and in the future could lead to vaccine escape, warn an international group of researchers in the UK and India. The researchers, led by scientists at the University of Cambridge, say that the impact of COVID-19 …
Researcher find a gene mutation connected to schizophrenia Kumar Jeetendra | March 24, 2021 Researchers at The Feinstein Institutes for Medical Research, in collaboration with Columbia University, have identified a gene mutation that could result in schizophrenia, a chronic brain disease that affects nearly 1 percent of the planet’s inhabitants. The findings, published in today in Neuron, could lead to novel treatment strategies. The research group, headed by Todd …
Researchers describe the systems that manage embryonic stem cells Kumar Jeetendra | March 26, 2021 Scientists at the Proteomics Core Unit of the Spanish National Cancer Research Centre (CNIO), headed by Javier Muñoz, have clarified the mechanisms, unknown to date, included in maintaining embryonic stem cells in the best possible condition for their use in regenerative medicine. The results, published in Nature Communications, helps to find novel stem-cell therapies for …
Small SARS-CoV-2 protein may have huge ramifications for future COVID-19 medicines Kumar Jeetendra | April 12, 2021 A very small protein of SARS-CoV-2, the coronavirus that gives rise to COVID-19, may have big implications for future therapies, according to a team of Penn State researchers. Using a novel toolkit of approaches, the scientists uncovered the first full structure of the Nucleocapsid (N) protein and discovered how antibodies from COVID-19 patients interact with …
NIAID sets up a clinical research organization to improve comprehension of child asthma Kumar Jeetendra | April 25, 2021 This nationwide network will conduct observational studies and clinical trials to improve understanding of asthma and develop prevention and treatment approaches tailored to children of low-income families residing in urban communities. NIAID plans to provide approximately $70 million over seven years to support the CAUSE network. This new initiative expands and extends NIAID’s long-standing attempts …
Researchers develop experimental direct-acting antiviral treatment to treat COVID-19 Kumar Jeetendra | May 18, 2021 An international team of scientists from the Menzies Health Institute Queensland (MHIQ) at Griffith University and from City of Hope, a research and treatment center for cancer, diabetes and other life-threatening diseases in the U.S., have developed an experimental direct-acting antiviral therapy to treat COVID-19. Conventional antivirals reduce symptoms and help people recover earlier. Examples …
New testing protocols for SARS-CoV-2 can handle a huge number of tests inside 48 hours Kumar Jeetendra | May 25, 2021 Researchers in the Vienna BioCenter designed a testing protocol for SARS-CoV-2 that can process tens of thousands of samples in less than 48 hours. The method, called SARSeq, is printed in the journal Nature Communications and might be adapted to many more pathogens. The COVID-19 pandemic has lasted more than a year and continues to …
Growing genomic research into different ancestries yields more and better outcomes Kumar Jeetendra | June 1, 2021 Currently published in Nature Genetics, their findings demonstrate that expanding research into different ancestries yields more and better results, in addition to ultimately benefitting global patient care. Up to now nearly 87 percent of genomic research of the type was conducted in Europeans. The global study team examined data across a wide assortment of cohorts, …
Study recognizes master regulator behind the improvement of antibody delivering cells Kumar Jeetendra | September 24, 2021 The main regulator that controls the production of antibody-producing cells was identified in a research conducted by scientists from Weill Cornell Medicine. These findings offer new insights into the functioning in the immunity system. It also can help to understand how tissues form and how cancers are triggered. The study, which was published on September. …
Novel antibody candidate shows powerful binding to different SARS-CoV-2 variant mutations Kumar Jeetendra | September 25, 2021 Twist Bioscience Corporation today reported that its internally-discovered antibody candidate TB202-3 (CoVIC-094), demonstrated potent binding to diverse SARS-CoV-2 variant mutations, including strains with the E484K, N501Y, D614G, Y453F and K417N mutations in pseudovirus assays, indicating this therapeutic antibody may be effective in treating many strains of COVID-19. The Coronavirus Immunotherapy Consortium (CoVIC) is an academic-industry-non-profit …
The Impact of Genomics on Drug Discovery: Advancements and Challenges Kumar Jeetendra | September 21, 2023 The entire collection of DNA in an organism is known as its genome. The human genome is made up of over 3 billion DNA base pairs, or letters, and is present in almost every single cell of the body. The study of genomes’ structure, function, evolution, mapping, and editing is the focus of the interdisciplinary …