Dexamethasone use could reduce immune checkpoint inhibitor viability in glioblastoma patients Kumar Jeetendra | November 25, 2020 Bottom Line: One of patients with glioblastoma getting an immune checkpoint inhibitor, people who obtained the corticosteroid dexamethasone at baseline for cerebral edema had significantly worse overall survival. Journal Where the Study was Released: Clinical Cancer Research, a journal of the American Association for Cancer Research Author: David A. Reardon, MD, clinical director of the …
New information shows empowering results for patients with neuro-degenerative blinding eye illness Kumar Jeetendra | December 16, 2020 New data published in the Journal Science Translational Medicine shows encouraging results in a worldwide clinical trial for patients diagnosed with the neuro-degenerative blinding eye disease; Leber Hereditary Optic Neuropathy (LHON. The disease is an inherited type of vision loss estimated to affect 1 in 30,000 to 50,000 individuals. LHON most often afflicts individuals with …
Researchers arrive at significant achievement in leishmaniasis immunization advancement Kumar Jeetendra | January 11, 2021 Scientists have taken an important step forward in creating a controlled human infection model to test leishmaniasis vaccines. The University of York-led study identified and characterized a new strain of Leishmania parasite that will form the basis of a new controlled human infection model for the disease which is transmitted by the bite of sand …
Novel biodegradable magnesium-composite tracheal stents for youngsters with airway obstruction Kumar Jeetendra | January 17, 2021 While it can be something a child is born with or caused by trauma, the condition may lead to a life-threatening emergency if untreated. Treatment, however, is challenging. Based on the severity, doctors will use a combination of endoscopic methods, surgical repair, tracheostomy, or deployment of stents to hold the airway open and enable breathing. …
Putatively juvenile dendritic cells may actuate hearty resistant reactions in young children Kumar Jeetendra | January 20, 2021 A study by Ludwig-Maximilians-Universitaet (LMU) in Munich researchers demonstrates that putatively immature dendritic cells found in young children are able to induce strong immune responses. Dendritic cells are a vital component of the innate immune system, which represents the body’s first line of defense against infectious agents and tumor cells. Their job is to trigger …
Second-generation double antibody shields from SARS-CoV-2 and its tried variations Kumar Jeetendra | January 25, 2021 Additionally, it prevents the virus from mutating to resist the treatment . Antibody-based immunotherapy was already proven to work against COVID-19 but faces two chief obstacles: it requires to work against the circulating viral variants; it has to avoid formation of new variants, that can rapidly ensue using a mechanism similar to that leading to …
Hydrogel injection could help fix harm to the heart muscle after heart attack Kumar Jeetendra | February 19, 2021 Researchers at CÚRAM, the SFI Research Centre for Medical Devices based at NUI Galway, and BIOFORGE Lab, at the University of Valladolid in Spain, have developed an injectable hydrogel which might help repair and prevent additional damage to the heart muscle following a heart attack occasion. The results of their research have only been published …
Microorganisms utilize vile methodology to vanquish antibody that battle cystic fibrosis Kumar Jeetendra | February 28, 2021 University of Montana researchers and their partners have found a slimy strategy used by bacteria to conquer antibiotics and other medications used to combat infections afflicting individuals with cystic fibrosis. Cystic fibrosis is a life-threatening illness which causes persistent lung infections and limits an individual’s ability to breathe over time. A frequent strain of bacteria, …
Compounds in green and black tea relax blood vessels by activating ion channel proteins Kumar Jeetendra | March 9, 2021 A new study from the University of California, Irvine shows that chemicals in both black and green tea relax blood vessels by activating ion channel proteins in the blood vessel wall. The discovery helps explain the antihypertensive properties of tea and could lead to the design of new blood pressure-lowering medications. Released in Cellular Physiology …
CN Bio presents the PhysioMimix™ OOC Multi-Organ Microphysiological System Kumar Jeetendra | March 17, 2021 CN Bio, a leading developer of single and multi-organ microphysiological systems (MPS), otherwise known as organ-on-a-chip (OOC), today announced the commercial launch of its new PhysioMimix™ OOC Multi-Organ MPS. The next-generation system unites CN Bio’s in vitro 3D liver model, whose phenotype and functions mimic that in vivo, with a range of other organs to …
Study assesses stem cells’ capacity to forestall significant reason for death in preterm newborn Kumar Jeetendra | April 21, 2021 A phase 2 clinical trial whose results were published today in STEM CELLS Translational Medicine might point to a way to conquer bronchopulmonary dysplasia (BPD), a significant cause of death in preterm infants. The study, conducted by researchers at Samsung Medical Center, Sungkyunkwan University and Asan Medical Center Children’s Hospital in Seoul, evaluates the efficacy …
FDA supports new medication for therapy of adults with chronic kidney infection Kumar Jeetendra | May 1, 2021 Today, the U.S. Food and Drug Administration accepted Farxiga (dapagliflozin) oral tablets to decrease the risk of kidney function decline, kidney failure, cardiovascular death and hospitalization for heart failure in adults with chronic kidney disease who are at risk of disease progression. Chronic kidney disease occurs when the kidneys are damaged and can’t filter blood …