MMR immunization could offer assurance against COVID-19 Kumar Jeetendra | June 20, 2020 Directing the MMR (measles, mumps, rubella) antibody could fill in as a preventive measure to hose septic aggravation related with COVID-19 disease, state a group of specialists in the current week’s mBio, a diary of the American Society for Microbiology. Long-term colleagues and life partners Dr. Paul Fidel, Jr., Department Chair, Oral and Craniofacial Biology, …
Jubilant Therapeutics reports preclinical information of double LSD1 and HDAC6 at AACR 2020 Kumar Jeetendra | June 23, 2020 Jubilant Therapeutics Inc., a biopharmaceutical organization propelling little particle modulators to address neglected clinical needs in oncology and immune system infections, today declared that preclinical information of double LSD1 and HDAC6 inhibitor JBI-802, will be introduced in a banner meeting at the American Association for Cancer Research (AACR) 2020 Virtual Annual Meeting II. The preclinical …
Nitric oxide treatment can be essential in the battle against COVID-19 Kumar Jeetendra | July 27, 2020 Nitric oxide therapy could be critical in the world’s struggle against SARS-CoV-2, the coronavirus which causes COVID-19, according to a review by the George Washington University (GW). Nitric oxide is an antimicrobial and anti inflammatory molecule with key roles in pulmonary arterial role in the context of viral infections as well as other pulmonary diseases. …
Custom smartwatch tracks sedate levels inside the body continuously Kumar Jeetendra | August 8, 2020 Engineers in the UCLA Samueli School of Engineering and their colleagues at Stanford School of Medicine have demonstrated that drug levels inside the body is able to be tracked in real time using a custom smartwatch which assesses the compounds found in sweat. This wearable technology can be incorporated into a more personalized approach to …
CRISPR-based framework smothers qualities identified with AAV antibody production Kumar Jeetendra | September 9, 2020 Gene therapy generally is based on viruses, such as adeno-associated virus (AAV), to deliver genes into a cell. In the event of CRISPR-based gene therapies, molecular scissors can then snip out a faulty gene, add in a missing arrangement or enact a temporary change in its expression, but the body’s immune response to AAV can …
Scientists study misleading impact in nausea therapy at the molecular level Kumar Jeetendra | September 28, 2020 The molecular bases of the placebo effect are poorly understood. A team headed by Ludwig-Maximilians-Universitaet (LMU) in Munich researcher Karin Meissner has now studied the phenomenon in the context of nausea, and identified specific proteins that correlate with its positive impact. The placebo effect seems to work wonders. In certain cases, administration of a’drug’ to …
New initiative identifies key parameters Inherent effective anti-tumor immunity Kumar Jeetendra | October 10, 2020 Neoantigens, tiny markers that arise from cancer mutations, flag cells as cancerous and could be the key to unlocking a new generation of immunotherapies. Targeting the”right” neoantigens – at a cancer vaccine or a cell treatment – has the promise to eliminate a patient’s cancer with minimal side effects. But countless mutations can exist in …
Trial ALS drug shows potential to drag out patient endurance Kumar Jeetendra | October 18, 2020 An experimental medicine that was recently shown to slow the progression of the neurodegenerative disease amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease, has now demonstrated the capacity to also prolong patient survival. The findings come from a clinical trial conducted by investigators at the Sean M. Healey & AMG Center for ALS at Massachusetts …
Researchers propose that antimalarial medications could be repurposed to treat COVID-19 Kumar Jeetendra | October 20, 2020 An international group of researchers believe there is enough evidence that anti-malarial drugs could be repurposed to treat COVID-19 and they need to be evaluated for efficacy in clinical trials. The review article, published online in Trends in Parasitology, summarizes the evidence for its antiviral and anti-inflammatory properties of particular anti-malarial drugs which could play …
Antenatal steroids improve preterm infant endurance in low-asset settings, discovers study Kumar Jeetendra | October 24, 2020 The results of a new clinical trial, published today in the New England Journal of Medicine, show that dexamethasone- a glucocorticoid used to treat many conditions, including rheumatic problems and severe COVID-19- may boost survival of premature babies when given to pregnant women at risk of premature birth in low-resource settings. The WHO ACTION-I trial …
Patients’ own stem cells can be utilized to develop new bones, study shows Kumar Jeetendra | November 23, 2020 A new, groundbreaking study from the University of Bergen (UiB) shows that a patients’ own stem cells can be used to grow new bone. This can potentially help millions of people who are partially edentulous and have inadequate bone for placement of dental implants. The Maxibone Project, coordinated by Pierre Layrolle, Inserm, University of Nantes, …
University of Sheffield and Pfizer dispatch new consortium to quicken improvement of ATMPs Kumar Jeetendra | November 24, 2020 The University of Sheffield and Pfizer have today (23 November 2020) established a new consortium which aims to standardize and accelerate the growth of Advanced Therapy Medicinal Products (ATMPs), allowing potentially transformative remedies to reach patients sooner. The new, five-year consortium, Accelerating Research and Innovation for Advanced Therapies (ARDAT), is supported by the Innovative Medicines …
