FDA issues emergency use approval for T-Detect COVID Test Kumar Jeetendra | March 7, 2021 Now, the U.S. Food and Drug Administration issued an emergency use authorization (EUA) for its T-Detect COVID Exam developed by Adaptive Biotechnologies. The T-Detect COVID Evaluation is a next generation sequencing established (NGS) test to assist in identifying people with an adaptive T cell immune response to SARS-CoV-2, indicating recent or prior infection with SARS-CoV-2. …
Deforestation in the Amazon builds variety of antibiotic-resistant bacteria Kumar Jeetendra | March 12, 2021 In Brazil, a study conducted by researchers affiliated with the University of São Paulo (USP) and collaborators showed that deforestation in the Amazon causes an increase in the diversity of antibiotic-resistant bacteria. An article on the study, published in Soil Biology and Biochemistry, compares the microorganisms that live in the land of indigenous forest with …
Study offers understanding into metabolic pathways hijacked by SARS-CoV-2 for viral replication Kumar Jeetendra | March 16, 2021 When SARS-CoV-2, the virus which causes COVID-19, infects a human cell, it quickly begins to replicate by seizing the cell’s existing metabolic machinery. The infected cells churn out thousands of viral genomes and proteins while halting the creation of their own sources. Researchers from Brigham and Women’s Hospital, Massachusetts General Hospital (MGH), and the Broad …
Scientists portray regions of DNA that sway MECP2 expression Kumar Jeetendra | March 19, 2021 Researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital (NRI) have identified and characterized two regions of DNA required for the proper expression of Mecp2/MECP2 in mice and humans. These findings, published in Genes & Development, are helping to shed light on the purpose of …
Intense openness of lung tissue to vape airborne lesserly affects gene expressionthan cigarette smoke Kumar Jeetendra | March 21, 2021 A new peer-reviewed study published in the journal Toxicological Research & Application reveals acute exposure of a 3D human bronchial tissue model to e-cigarette aerosol has minimal impact on gene expression in contrast to smoke from combustible cigarettes. The study included sub-cytotoxic vulnerability to cells in a 3D human bronchial model (MucilAirTM) to nicotine-containing vape …
Study maps design and system of a membrane enzyme that assumes part in inflammation, cancer Kumar Jeetendra | March 21, 2021 Most drugs operate via the membranes that surround the body’s cells. The analysis, which is printed in the journal Nature Communications, can make a significant contribution to the development of potential drugs. The cells’ equal to organs, the organelles, are enclosed by membranes. Embedded in the cell’s external and internal membranes are proteins that regulate …
Universal microplastics can become ‘centers’ for antibiotic-resistant bacteria Kumar Jeetendra | March 22, 2021 It is estimated that an average-sized wastewater treatment plant serving approximately 400,000 inhabitants will discharge up to 2,000,000 microplastic particles to the environment every day. Yet, researchers are still learning the ecological and human health impact of these ultra-fine plastic particles, less than 5 millimeters in length, found in everything from makeup, toothpaste and clothes …
Researcher find a gene mutation connected to schizophrenia Kumar Jeetendra | March 24, 2021 Researchers at The Feinstein Institutes for Medical Research, in collaboration with Columbia University, have identified a gene mutation that could result in schizophrenia, a chronic brain disease that affects nearly 1 percent of the planet’s inhabitants. The findings, published in today in Neuron, could lead to novel treatment strategies. The research group, headed by Todd …
Researchers describe the systems that manage embryonic stem cells Kumar Jeetendra | March 26, 2021 Scientists at the Proteomics Core Unit of the Spanish National Cancer Research Centre (CNIO), headed by Javier Muñoz, have clarified the mechanisms, unknown to date, included in maintaining embryonic stem cells in the best possible condition for their use in regenerative medicine. The results, published in Nature Communications, helps to find novel stem-cell therapies for …
Imbalanced bacterial community in the gums connected to Alzheimer’s infection biomarker Kumar Jeetendra | April 12, 2021 Older adults with more harmful than healthy bacteria in their gums are more likely to have evidence for amyloid beta–a key biomarker for Alzheimer’s disease–in their cerebrospinal fluid (CSF), according to new research from NYU College of Dentistry and Weill Cornell Medicine. However, this imbalance in oral bacteria was not associated with another Alzheimer’s biomarker …
Genetic variants that sway protein restricting in immune cells can cause autoimmune disease Kumar Jeetendra | April 17, 2021 Certain genetic variants that cause modified protein binding in immune cells, are also seen in people at high risk of some autoimmune diseases, new research has found. Researchers from the Wellcome Sanger Institute, Josep Carreras Leukaemia Research Institute in Spain, and the MRC London Institute of Medical Sciences (LMS) discovered that specific genetic variants, which …
RNA secondary constructions can contribute strongly to gene guideline, research shows Kumar Jeetendra | April 22, 2021 A group of scientists from Russia studied the function of double-stranded fragments of the aging RNA and revealed that the interaction between distant areas of the RNA can modulate gene expression. The study was published in Nature Communications. At school, we learn that DNA is double-stranded and RNA is single-stranded, but that isn’t entirely true. …
