Second-generation double antibody shields from SARS-CoV-2 and its tried variations Kumar Jeetendra | January 25, 2021 Additionally, it prevents the virus from mutating to resist the treatment . Antibody-based immunotherapy was already proven to work against COVID-19 but faces two chief obstacles: it requires to work against the circulating viral variants; it has to avoid formation of new variants, that can rapidly ensue using a mechanism similar to that leading to …
Study shows why children of obese moms have inclination to create metabolic illnesses Kumar Jeetendra | January 27, 2021 A Brazilian study published in the journal Molecular Human Reproduction helps understand why overweight mothers often have children with a propensity to develop metabolic disease during their lifetime, according to previous research. According to the authors,”transgenerational transmission of metabolic disorders” may be associated with Mfn2 deficiency in the mother’s oocytes (immature eggs). Mfn2 refers to …
New gene based vaccine procedure gets award from the Bill and Melinda Gates Foundation Kumar Jeetendra | January 29, 2021 The AAVCOVID vaccine application, a novel gene-based vaccine plan that utilizes an adeno-associated virus (AAV) vector, was granted an award for up to $2.1 million from the Bill & Melinda Gates Foundation. The grant will assist the effort to bring further preclinical validation into the AAV vaccine platform. An AAVCOVID vaccine candidate is set to …
Hereditary components of human gut microbiota are key to wellbeing Kumar Jeetendra | February 6, 2021 Neanderthals’ gut microbiota already contained some beneficial micro-organisms that are also found within our own intestine. An international research group headed by the University of Bologna achieved this result by extracting and analyzing ancient DNA from 50,000-year-old fecal sediments sampled at the archaeological site of El Salt, near Alicante (Spain). Published in Communication Biology, their …
Novel finding could prompt better medicines for Type 1 and Type 2 diabetes Kumar Jeetendra | February 13, 2021 Monash University researchers have discovered the barrier to β-cell (beta mobile ) regeneration which could pave the way for improved treatments for diabetes and diseases that involve organ and tissue damage. The human body does not repair itself very well, with our liver the only organ that can regenerate economically. We have limited capacity to …
Utilizing a cell phone based microscope for recognizing single molecules and diagnosing infections Kumar Jeetendra | February 14, 2021 Biomarkers play a central role in the identification of disease and evaluation of its course. Among the markers now in use are genes, hormones, proteins, lipids and other types of molecules. Biomarkers can be found in the bloodstream, in cerebrospinal fluid, urine and various types of tissues, but many of them have one thing in …
Researchers concentrate how a single gene alteration may have isolated modern humans from extinct hominins Kumar Jeetendra | February 16, 2021 As a professor of pediatrics and molecular and cellular medicine at University of California San Diego School of Medicine, Alysson R. Muotri, PhD, has long studied how the brain develops and what goes wrong in neurological disorders. For nearly as long, he has also been curious about the evolution of the human brain -; what …
Researchers utilize funtional test to quantify the impact of inhertited varient in BRCA2 acancer gene Kumar Jeetendra | February 21, 2021 Researchers at Mayo Clinic have combined results from a functional test measuring the effect of inherited variations in the BRCA2 breast and ovarian cancer gene with clinical information from women who received genetic testing to determine the clinical importance of many BRCA2 variants of uncertain significance (VUS). The findings were published today in a study …
Retroviruses attacking the koala germline add to high malignant growth rates Kumar Jeetendra | February 26, 2021 Koalas are facing multiple ecological and health issues which threaten their survival. Together with habitat loss – accelerated by last year’s devastating bush fires — domestic dog attacks and road accidents, they suffer from fatal chlamydial infections and extremely high frequency of cancer. The results are reported in the journal Nature Communications. The koala retrovirus …
Microorganisms utilize vile methodology to vanquish antibody that battle cystic fibrosis Kumar Jeetendra | February 28, 2021 University of Montana researchers and their partners have found a slimy strategy used by bacteria to conquer antibiotics and other medications used to combat infections afflicting individuals with cystic fibrosis. Cystic fibrosis is a life-threatening illness which causes persistent lung infections and limits an individual’s ability to breathe over time. A frequent strain of bacteria, …
Study shows the effect of ‘reverse antibiotic’ on gram-negative bacteria Kumar Jeetendra | March 5, 2021 Researchers from Skoltech and MSU have investigated antibiotic nybomycin that could prove effective against bacteria resistant to other antibiotics. Their research was published in the journal Antimicrobial Agents and Chemotherapy. All bacterial cells contain topoisomerases, a significant group of enzymes that help deal with spatial problems stemming from bacterial cell division related to circular DNA …
A little sensor can be utilized for fast recognition of RNA and DNA Kumar Jeetendra | March 6, 2021 In less than a second, a small sensor used in brain chemistry research can detect the key molecules that provide the genetic instructions for life, RNA, and DNA, a new study from American University shows. The AU researchers believe a sensor is a helpful tool for scientists engaged in clinical research to quantify DNA metabolism, …