BioChromato’s RAPID Slit Seals offer significant advantages over customary silicone mats

Overview

• Post By : Kumar Jeetendra


• Source: BioChromato Inc.


• Date: 17 Sep,2020

BioChromato Inc. reports that the pharmacokinetics department in a leading Japanese pharmaceutical company has found that RAPID Slit Seals provide significant benefits when compared with conventional silicone mats for maintaining the integrity of microplate samples.

In their drive to identify new drug entities the pharmacokinetics division use a mass spectrometer served by an autosampler managing biological samples ready in 96-well microplates. Traditionally the section used silicone mats to keep the integrity of the microplate samples. While this approach worked well – it was expensive and the silcone plate seals needed to be carefully washed before reuse as contamination from the biological samples handled was a concern.

Switching to disposible RAPID Slit Seals from BioChromato the pharmacokinetics division has eliminated the prior biological contamination problem and significantly reduced the cost per analysis.

In addition, the pharmaceutical company revealed that the autosampler injection hole in the disposible plate seals rapidly closes after each injection, making it an perfect closure for samples which may be selected for further analysis. Despite samples stored for many days in volatile solvents, such as acetonitrile, the RAPID Slit Seals were found to minimize solvent loss through evaporation ensuring sample integrity and the validity of replicate investigations.

Proven in labs worldwide, RAPID Slit Seal is a proprietary self-closing microplate seal that contributes to its original state even when punched with an HPLC or LC/MS autosampler. As a result, loss of volatile solvents from the valuable samples is minimized.