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    Infectious Diseases

    Researchers discover proof that SARS-CoV-2 infects cells in the mouth

    An international group of scientists has discovered evidence that SARS-CoV-2, the virus that causes COVID-19, infects cells in the mouth. While it’s well known that the upper airways and lungs are primary sites of SARS-CoV-2 disease, there are clues the virus can infect cells in different parts of the body, like the digestive system, blood

    NIAID sets up a clinical research organization to improve comprehension of child asthma

    This nationwide network will conduct observational studies and clinical trials to improve understanding of asthma and develop prevention and treatment approaches tailored to children of low-income families residing in urban communities. NIAID plans to provide approximately $70 million over seven years to support the CAUSE network. This new initiative expands and extends NIAID’s long-standing attempts

    Novel platform has potential to detect many disease-related biomarkers in just one test

    Most conventional molecular diagnostics usually detect only one disease-related biomarker. Fantastic examples are the PCR tests now used to diagnose COVID-19 by detecting a particular sequence from SARS-CoV-2. Such so-called singleplex methods give reliable results because they are”calibrated” to a single biomarker. However, determining whether a patient is infected with a new SARS-CoV-2 version or

    Study gives significant knowledge to forestalling worldwide pandemics

    Whether it’s plankton exposed to parasites or people exposed to pathogens, a host’s initial immune response plays an integral role in determining whether infection occurs and to what level it spreads within a population, new University of Colorado Boulder research indicates. From parasitic flatworms transmitted by snails into individuals in developing nations, to zoonotic spillover

    Researchers develop experimental direct-acting antiviral treatment to treat COVID-19

    An international team of scientists from the Menzies Health Institute Queensland (MHIQ) at Griffith University and from City of Hope, a research and treatment center for cancer, diabetes and other life-threatening diseases in the U.S., have developed an experimental direct-acting antiviral therapy to treat COVID-19. Conventional antivirals reduce symptoms and help people recover earlier. Examples

    Scientists find how Rift Valley fever virus enters cells

    Rift Valley fever virus causes economically tragic hemorrhagic outbreaks in livestock, including cattle, goats, and sheep. The mosquito-borne infections can lead to the spread of infection to people who work with animals that are dying or dead often causing many human infections as well as many deaths. Rift Valley fever, for which there isn’t a

    Novel antibody candidate shows powerful binding to different SARS-CoV-2 variant mutations

    Twist Bioscience Corporation today reported that its internally-discovered antibody candidate TB202-3 (CoVIC-094), demonstrated potent binding to diverse SARS-CoV-2 variant mutations, including strains with the E484K, N501Y, D614G, Y453F and K417N mutations in pseudovirus assays, indicating this therapeutic antibody may be effective in treating many strains of COVID-19. The Coronavirus Immunotherapy Consortium (CoVIC) is an academic-industry-non-profit

    How Proteolytic Cleavage Affects Cell Function

    An impact that could be devastating to human life can occur as a consequence of this process and is, thinking in an ecological way, can ensure the continuity of life. The phenomenon of nature is proteolytic cleavage that can most definitely be defined as a double edged sword. It certainly decides the future of humans