Novel finding could prompt better medicines for Type 1 and Type 2 diabetes Kumar Jeetendra | February 13, 2021 Monash University researchers have discovered the barrier to β-cell (beta mobile ) regeneration which could pave the way for improved treatments for diabetes and diseases that involve organ and tissue damage. The human body does not repair itself very well, with our liver the only organ that can regenerate economically. We have limited capacity to …
Utilizing a cell phone based microscope for recognizing single molecules and diagnosing infections Kumar Jeetendra | February 14, 2021 Biomarkers play a central role in the identification of disease and evaluation of its course. Among the markers now in use are genes, hormones, proteins, lipids and other types of molecules. Biomarkers can be found in the bloodstream, in cerebrospinal fluid, urine and various types of tissues, but many of them have one thing in …
Researchers concentrate how a single gene alteration may have isolated modern humans from extinct hominins Kumar Jeetendra | February 16, 2021 As a professor of pediatrics and molecular and cellular medicine at University of California San Diego School of Medicine, Alysson R. Muotri, PhD, has long studied how the brain develops and what goes wrong in neurological disorders. For nearly as long, he has also been curious about the evolution of the human brain -; what …
Study discoveries help clarify the variety of cancers in various Li-Fraumeni patients Kumar Jeetendra | February 23, 2021 The most frequently mutated gene in human cancers is called p53. Patients with Li-Fraumeni syndrome, which is a rare disorder that increases the risk of developing several kinds of cancer, often have an increased risk to develop cancers at early ages if they inherit p53 mutations. Recent studies suggest that some people with inherited p53 …
Retroviruses attacking the koala germline add to high malignant growth rates Kumar Jeetendra | February 26, 2021 Koalas are facing multiple ecological and health issues which threaten their survival. Together with habitat loss – accelerated by last year’s devastating bush fires — domestic dog attacks and road accidents, they suffer from fatal chlamydial infections and extremely high frequency of cancer. The results are reported in the journal Nature Communications. The koala retrovirus …
Study shows the effect of ‘reverse antibiotic’ on gram-negative bacteria Kumar Jeetendra | March 5, 2021 Researchers from Skoltech and MSU have investigated antibiotic nybomycin that could prove effective against bacteria resistant to other antibiotics. Their research was published in the journal Antimicrobial Agents and Chemotherapy. All bacterial cells contain topoisomerases, a significant group of enzymes that help deal with spatial problems stemming from bacterial cell division related to circular DNA …
Diphtheria is developing to get antibiotic-resistant safe and could prompt vaccine escape Kumar Jeetendra | March 8, 2021 Diphtheria – a comparatively easily-preventable infection – is evolving to become immune to a range of types of antibiotics and in the future could lead to vaccine escape, warn an international group of researchers in the UK and India. The researchers, led by scientists at the University of Cambridge, say that the impact of COVID-19 …
Novel device can add or eliminate sugar from proteins Kumar Jeetendra | March 12, 2021 Sugar has been called “evil,” “toxic,” and “poison.” But the body needs sugars, also. Sugar molecules help cells recognize and fight germs and viruses, shuttle proteins from cell to cell, and make sure those proteins function. Too much or too small can give rise to a range of maladies, including neurodegenerative diseases like Alzheimer’s, diabetes, …
Deforestation in the Amazon builds variety of antibiotic-resistant bacteria Kumar Jeetendra | March 12, 2021 In Brazil, a study conducted by researchers affiliated with the University of São Paulo (USP) and collaborators showed that deforestation in the Amazon causes an increase in the diversity of antibiotic-resistant bacteria. An article on the study, published in Soil Biology and Biochemistry, compares the microorganisms that live in the land of indigenous forest with …
Scientists portray regions of DNA that sway MECP2 expression Kumar Jeetendra | March 19, 2021 Researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital (NRI) have identified and characterized two regions of DNA required for the proper expression of Mecp2/MECP2 in mice and humans. These findings, published in Genes & Development, are helping to shed light on the purpose of …
Secret genetic defects can prompt a wide range of serious illnesses Kumar Jeetendra | March 20, 2021 For the first time researchers from Hebrew University of Jerusalem, Radboudumc, Maastricht UMC+ and worldwide colleagues have gained insight to the”hidden genetic defects” of the general European population. This is important as these defects, if inherited from the father and mother, can result in all kinds of disorders in their children. Research in the Dutch …
Intense openness of lung tissue to vape airborne lesserly affects gene expressionthan cigarette smoke Kumar Jeetendra | March 21, 2021 A new peer-reviewed study published in the journal Toxicological Research & Application reveals acute exposure of a 3D human bronchial tissue model to e-cigarette aerosol has minimal impact on gene expression in contrast to smoke from combustible cigarettes. The study included sub-cytotoxic vulnerability to cells in a 3D human bronchial model (MucilAirTM) to nicotine-containing vape …
