Subscribe to our Newsletters !!
Climate change is very disruptive to the Amazon ra
By 2024, there are certain things you need to do i
Insects that are given more attention and reverenc
Alembic Pharmaceuticals Limited appoints Mr. Manis
The importance of comparing the treatment of asthm
It is important to understand that natural remedie
Dear Readers, Welcome to the latest issue of The Magazine
High flow oxygen therapy is a form of respiratory support used in the hospital where oxygen, often in conjunction with compressed air and humidification, is delivered to a patient at rates of flow higher than that delivered traditionally in oxygen therapy.
Eliminate most of the anatomic dead space Create a reservoir with high FiO2 in the nasal cavity Improve gas exchange Significantly reduce the work of breathing High flow oxygen therapy can minimize the inspiratory resistance associated with the nasopharynx by providing nasopharyngeal gas flows that match or exceed a patient’s peak inspiratory flow. The resulting reduction in resistance translates into a decrease in resistive work of breathing.
Nebulized drug administration during high flow oxygen therapy helps you improve therapy efficiency, for example in cases of bronchospasm or chronic hypercapnia.
Aerosol therapy during the use of High Flow Nasal Cannula (HFNC) can be provided by the Aerogen Solo in line with a variety of HFNC systems, delivering aerosol directly through the nasal cannula. This technique allows aerosol delivery without interruption of oxygen flow and pressure and is more effective than placement of an aerosol mask over the nasal cannula. Preliminary studies have demonstrated sub-optimal delivery of aerosol with the placement of aerosol masks over the cannula compared to taking the cannula off to administer aerosol therapy.
Initial studies have demonstrated that the Aerogen Solo can provide effective aerosol therapy through the cannula of a HFNC system7, 31, 32. Ari et al. studied aerosol delivery in paediatric patients and showed that an inhaled dose of 11% was achievable at a gas flow rate of 3L/min. The effect of flow and gas type does modify the aerosol deposition where heliox and lower flow rates have a favourable effect on aerosol dose. More recent research into adult HFNC showed that placing the
Aerogen Solo before the humidifier provided optimal aerosol therapy in comparison to two small volume nebulisers.
Reminiac at al. commented that the Aerogen Solo “was associated with high nebulisation efficiency, a high fraction of aerosol made of particle with a diameter of 0.4 to 4.4 μm, a shorter nebulisation duration, and the absence of added gas flow” which could potentially influencing the inspired oxygen fraction8.
A lung dose of between 2-10% were achieved at flows rates 30, 45, and 60 L/min and aerosol delivered was greater with distressed breathing than with normal breathing.
Aerogen provides superior aerosol therapy within the intensive care environment during ventilation, NIV, HFNC and with spontaneously breathing patients. In addition to the optimal performance, substantial cost savings have also been acknowledged when hospitals make the transition to the device.
Note: The Article is compiled by Kamal Kishore, Business Manager, Aerogen India
