Limits for N-Nitrosamines in Drug Products and their Structure-Activity Relationship Kumar Jeetendra | July 10, 2024 The Threshold Limits for N-nitrosamines underscore the critical balance between safety and risk in pharmaceuticals, with a class-specific concern for highly carcinogenic compounds. Threshold Limits for N-nitrosamines Based on the Threshold of Toxicological Concern (TTC) concept described in ICH M7 (1), most mutagenic impurities are limited to a dose of 1.5 µg/day which corresponds to …
Validating HPLC results obtained using any solvent Kumar Jeetendra | July 10, 2024 TESTA Analytical has published a new technical study that demonstrates the utility of its non-invasive liquid flowmeter for validating the performance of HPLC systems across a wide range of different solvents. HPLC separation protocols employ many different solvents to accommodate the unique properties of different analytes. Ensuring consistent elution profiles is a key requirement to …
Selecting Laboratory Reagents: Best Practices and Key Considerations Kumar Jeetendra | July 8, 2024 Laboratory reagents actually serves as the basic for scientific experiments hence they determine the authenticity and reproducibility of research findings. There are several factors to consider before settling on any reagent including its level of purity, grade and supplier reliability. The guide covers various crucial aspects in selection laboratory reagents; therefore, it offers insight to …
The Pill of Tomorrow: Innovations in Drug Delivery Systems Kumar Jeetendra | July 8, 2024 We stand at the threshold of a new era in medical science where the phrase “take two pills and call me in the morning” is becoming more sophisticated. Drug delivery systems have advanced to this point that how drugs are administered, absorbed and monitored within the body has completely changed thus promising to revolutionize healthcare …
The Ultimate Guide to Choosing the Right Laboratory Materials Kumar Jeetendra | July 4, 2024 To ensure that scientific experiments are conducted safely, accurately, efficiently and reproducibly, it is crucial to choose appropriate laboratory materials. This exhaustive manual includes critical points to consider when determining the right materials for use which include; their types, applications and maintenance among others. When putting up a new lab or updating existing equipment, you …
Silicone Tubing: Revolutionizing Applications Across Multiple Sectors Kumar Jeetendra | July 4, 2024 Silicone tubing has emerged as a versatile and essential component in various industries, renowned for its flexibility, durability, and biocompatibility. From medical devices to food processing, and aerospace to consumer electronics, silicone tubing is transforming how we approach complex challenges. This article delves into the diverse applications of silicone tubing, highlighting its unique properties that …
New class of drugs effective against SARS-COV-2 and many RNA viruses Kumar Jeetendra | July 4, 2024 Researchers may have discovered a new class of front-line drugs that can both prevent the spread of new viruses and limit their severity. In laboratory tests, the already available treatments showed promise in fighting a range of existing RNA viruses, including SARS-Cov-2 and other human coronaviruses. Scientists have identified a new class of drugs with …
Precision in Practice: Sartorius Weighing Solutions Revolutionizing Pharmaceutical Manufacturing Kumar Jeetendra | July 4, 2024 We had the pleasure of interviewing Mr. Somnath, a distinguished professional with a rich background in science and management. Graduating from Mithila University, India, with a degree in science and furthering his education with a PGDBM from the Institute of Management Education, Mr. Somnath has accumulated over 13 years of invaluable experience in the analytical …
From Lab to Market :Optimizing QC for Pharmaceutical Product Development Kumar Jeetendra | July 4, 2024 Quality control (QC) is crucial in product development due to health, safety, regulatory needs, and efficacy. To make QC procedures from the lab to the market more efficient requires a combination of rigorous testing using state of the art technology and strategic planning amongst other considerations for navigating drug development complexities. The Path of Quality …
Navigating Regulatory Challenges : Microbiology QC in the Pharma Industry Kumar Jeetendra | July 4, 2024 Strict regulatory requirements are currently facing the pharmaceutical industry, especially in microbiology quality control (QC). For assurance of safety and efficacy of pharmaceutical products, rigorous microbiological testing is important for detection and control of contamination risks. Below is an overview of the principal regulatory challenges as well as strategies on effective microbiology QC within pharma …
Innovations in Lab Cooling: JULABO Immersion Coolers at the Forefront Kumar Jeetendra | May 27, 2024 In the constantly evolving world of laboratory technology, efficient and reliable cooling solutions are critical for a wide range of applications. Traditional cooling methods, while effective, often come with limitations such as high-water consumption and bulky equipment. Enter JULABO Immersion Coolers – a revolutionary solution that addresses these challenges with cutting-edge design and functionality. Introducing …
BioBased 96-well PCR Plates – Now also semi-skirted Kumar Jeetendra | May 16, 2024 Our customers depend on the high performance and reliability of the plates used in their high-throughput processes. However, increased throughput results in a higher carbon footprint due to the use of single-use plates made from fossil-based plastics. There is now a growing demand for more sustainability. Eppendorf’s biobased consumables open up new doors to make …
