Small SARS-CoV-2 protein may have huge ramifications for future COVID-19 medicines Kumar Jeetendra | April 12, 2021 A very small protein of SARS-CoV-2, the coronavirus that gives rise to COVID-19, may have big implications for future therapies, according to a team of Penn State researchers. Using a novel toolkit of approaches, the scientists uncovered the first full structure of the Nucleocapsid (N) protein and discovered how antibodies from COVID-19 patients interact with …
FDA denies EUA for monoclonal antibody treatment bamlanivimab to treat patients with COVID Kumar Jeetendra | April 18, 2021 Now, the U.S. Food and Drug Administration revoked the emergency use authorization (EUA) that allowed for the investigational monoclonal antibody treatment bamlanivimab, when administered alone, to be utilized for treating mild-to-moderate COVID-19 in adults and certain pediatric patients. Based on its ongoing analysis of emerging scientific data, specifically the sustained increase of SARS-CoV-2 viral variants …
New hereditarily encoded sensor recognizes drugs of abuse Kumar Jeetendra | April 29, 2021 A genetically encoded sensor to detect hallucinogenic compounds has been developed by researchers at the University of California, Davis. Named psychLight, the sensor could be used in discovering new treatments for mental illness, in neuroscience research and to detect drugs of abuse. The work is published April 28 in the journal Cell. Compounds associated with …
Researchers examine signal necrotic cells that prompt phagocytic cells to overwhelm the dying cell Kumar Jeetendra | May 8, 2021 As people keep their homes clean and clutter in check, a crew of cells within the body is in charge of clearing the waste that the body generates, including cells that are dying. The housekeeping cells remove unwanted material by a process called phagocytosis, which literally means’eating cells’ “Phagocytosis is quite important for the body’s …
Scientists find how Rift Valley fever virus enters cells Kumar Jeetendra | September 24, 2021 Rift Valley fever virus causes economically tragic hemorrhagic outbreaks in livestock, including cattle, goats, and sheep. The mosquito-borne infections can lead to the spread of infection to people who work with animals that are dying or dead often causing many human infections as well as many deaths. Rift Valley fever, for which there isn’t a …
Study recognizes master regulator behind the improvement of antibody delivering cells Kumar Jeetendra | September 24, 2021 The main regulator that controls the production of antibody-producing cells was identified in a research conducted by scientists from Weill Cornell Medicine. These findings offer new insights into the functioning in the immunity system. It also can help to understand how tissues form and how cancers are triggered. The study, which was published on September. …
Novel antibody candidate shows powerful binding to different SARS-CoV-2 variant mutations Kumar Jeetendra | September 25, 2021 Twist Bioscience Corporation today reported that its internally-discovered antibody candidate TB202-3 (CoVIC-094), demonstrated potent binding to diverse SARS-CoV-2 variant mutations, including strains with the E484K, N501Y, D614G, Y453F and K417N mutations in pseudovirus assays, indicating this therapeutic antibody may be effective in treating many strains of COVID-19. The Coronavirus Immunotherapy Consortium (CoVIC) is an academic-industry-non-profit …
Nano-bubbles containing ACE2 protein can hinder contamination from wide strains of SARS-CoV-2 Kumar Jeetendra | January 21, 2022 Northwestern Medicine and The University of Texas MD Anderson Cancer Center discovered that natural nano-bubbles containing ACE2 protein (evACE2) were found in the blood of COVID-19 victims. They also discovered that these particles could block infection by broad strains of SARS/CoV-2 virus. Scientists said that the evACE2 acts in the body as a decoy and …
