Study shows why children of obese moms have inclination to create metabolic illnesses Kumar Jeetendra | January 27, 2021 A Brazilian study published in the journal Molecular Human Reproduction helps understand why overweight mothers often have children with a propensity to develop metabolic disease during their lifetime, according to previous research. According to the authors,”transgenerational transmission of metabolic disorders” may be associated with Mfn2 deficiency in the mother’s oocytes (immature eggs). Mfn2 refers to …
Hereditary components of human gut microbiota are key to wellbeing Kumar Jeetendra | February 6, 2021 Neanderthals’ gut microbiota already contained some beneficial micro-organisms that are also found within our own intestine. An international research group headed by the University of Bologna achieved this result by extracting and analyzing ancient DNA from 50,000-year-old fecal sediments sampled at the archaeological site of El Salt, near Alicante (Spain). Published in Communication Biology, their …
Study discoveries help clarify the variety of cancers in various Li-Fraumeni patients Kumar Jeetendra | February 23, 2021 The most frequently mutated gene in human cancers is called p53. Patients with Li-Fraumeni syndrome, which is a rare disorder that increases the risk of developing several kinds of cancer, often have an increased risk to develop cancers at early ages if they inherit p53 mutations. Recent studies suggest that some people with inherited p53 …
Scientists portray regions of DNA that sway MECP2 expression Kumar Jeetendra | March 19, 2021 Researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital (NRI) have identified and characterized two regions of DNA required for the proper expression of Mecp2/MECP2 in mice and humans. These findings, published in Genes & Development, are helping to shed light on the purpose of …
Researchers enlighten how a few antibodies can viably disable ebolaviruses Kumar Jeetendra | April 18, 2021 Some survivors of ebolavirus outbreaks create antibodies that may broadly neutralize those viruses–and today , scientists at Scripps Research have illuminated how these antibodies can disable the viruses so efficiently. The insights might be helpful for developing effective treatments. Ebolavirus is a family of often-deadly viruses that includes Ebola virus and lots of lesser-known viruses …
Scientists distinguish new compound that may forestall heart arrhythmia risk from basic drugs Kumar Jeetendra | May 16, 2021 Dozens of commonly used drugs, including antibiotics, antinausea and anticancer medications, have a potential side effect of lengthening the electrical event that causes regeneration, creating an irregular heartbeat, or cardiac arrhythmia called acquired Long QT syndrome. While safe in their current dosages, some of these drugs might have a more therapeutic benefit at higher doses, …
Scientists test a library of lipid-based compounds to empower safe RNA drug delivery to Lungs Kumar Jeetendra | July 30, 2021 Japan’s Hokkaido University researchers created and tested a collection of lipid-based compounds in order to deliver RNA drugs safely and effectively to the lungs. The findings were published in Materials Horizons. The COVID-19 pandemic response made it all more familiar with RNA vaccines. These vaccines carry genetic code into the cells, which triggers the production …