Mass spectrometry shows potential for fast SARS-CoV-2 recognition Kumar Jeetendra | August 10, 2020 A team from SPI in Marcoule discovered by mass spectrometry, in just 3 minutes and without specific reagents, signature peptides of the SARS-CoV-2 virus in clinical samples (nasopharyngeal swabs). It hence gives a proof of concept concerning the usage of the technique as a potential option to PCR, now the reference process. Quick but nonetheless …
Scientists distinguish new method that causes leukemia Kumar Jeetendra | August 13, 2020 Every year, 1.1 million new cases of blood cancers are diagnosed globally. Currently, chemotherapy remains the most common and efficient plan of treatment. On the other hand, the development of aggressive types of leukemia in adults stimulates a need for early detection and new therapeutic approaches to achieve better clinical outcomes. In a novel step …
Propelled investigation offers new experiences into safe framework’s job in serious COVID-19 Kumar Jeetendra | August 14, 2020 By conducting complex diagnoses of immune system stimulation in patients with acute COVID-19, researchers at Karolinska Institutet have managed to spot several cell types that play a key part in the immune reaction to the new coronavirus and the hyperinflammation found in severe cases of the disease. The results are published in the scientific journal …
Examination shows how a protein prevents cells from assaulting their own DNA Kumar Jeetendra | August 20, 2020 Viruses multiply by injecting their DNA into a host cell. Once it passes the intracellular fluid, then this foreign substance triggers a defense mechanism referred to as the cGAS-STING pathway. This, in turn, binds to another protein named Stimulator of Interferon Genes (STING), which induces an inflammatory immune reaction. From time to time, the material …
Oxytocinergic and vasopressinergic substances in the mind are associated with managing social conduct Kumar Jeetendra | September 4, 2020 In humans, mutations of this gene cause Rett syndrome, a rare disorder of the neural development that causes, among other ailments, a reduction of language and of their capacity to roam, traits of autistic diseases and epilepsy. Nonapeptides, peptide chains with nine amino acids like oxytocin and vasopressin, are found in the cerebral nuclei that …
CRISPR-based framework smothers qualities identified with AAV antibody production Kumar Jeetendra | September 9, 2020 Gene therapy generally is based on viruses, such as adeno-associated virus (AAV), to deliver genes into a cell. In the event of CRISPR-based gene therapies, molecular scissors can then snip out a faulty gene, add in a missing arrangement or enact a temporary change in its expression, but the body’s immune response to AAV can …
Key China COVID-19 examination delivered results that affected ensuing exploration on Covid Kumar Jeetendra | September 18, 2020 Crucial China COVID-19 study produced results that Affected subsequent research on coronavirus Early in the start of the COVID-19 pandemic, a small study in China produced results that affected subsequent research on the virus. Researchers at the University of Cincinnati used the same research parameters on a much larger patient population and reached completely different …
PC model disentangles puzzle behind serious aggravation in individuals with COVID-19 Kumar Jeetendra | September 29, 2020 A study from the University of Pittsburgh School of Medicine and Cedars-Sinai addresses a mystery first raised in March: Why do some people with COVID-19 develop severe inflammation? The research shows how the molecular arrangement and arrangement of the SARS-CoV-2 spike protein–part of the virus that causes COVID-19–could be behind the inflammatory syndrome cropping up …
CBD could lessen lung harm brought about by COVID-19 Kumar Jeetendra | October 19, 2020 One way CBD appears to reduce the”cytokine storm” that damages the lungs and kills many individuals with COVID-19 is by enabling an increase in levels of a natural peptide called apelin, which is proven to reduce inflammation and whose levels are dramatically reduced in the face of this storm. Dental College of Georgia and Medical …
Boosting a characteristic cell cycle could bring down ventilator-related lung damage Kumar Jeetendra | January 12, 2021 An unfortunate truth about the use of mechanical ventilation to save the lives of patients in respiratory distress is that the pressure used to inflate the lungs is very likely to cause further lung damage. In a new study, scientists identified a molecule that’s produced by immune cells during mechanical ventilation to try to decrease …
Scientists find uncommon hereditary disorder that influences the brain, heart and facial highlights Kumar Jeetendra | January 21, 2021 Researchers at the National Institutes of Health have discovered a new genetic disorder characterized by developmental delays and malformations of the brain, heart and facial features. Named linkage-specific-deubiquitylation-deficiency-induced embryonic defects syndrome (LINKED), it is caused by a mutated version of the OTUD5 gene, which interferes with key molecular actions in embryo development. The findings indicate …
World’s first completely reversible control of the circadian clock Kumar Jeetendra | January 26, 2021 The Nagoya University Institute of Transformative Bio-Molecules (WPI-ITbM) research team of Designated Associate Professor Tsuyoshi Hirota, Postdoctoral Fellow Simon Miller, Professor Kenichiro Itami and grad student Tsuyoshi Oshima (Research Fellowship for Young Scientists, JSPS), in collaboration with the team of Professor Ben Feringa and Postdoctoral Fellow Dušan Kolarski of Groningen University in the Netherlands, have …