RNA secondary constructions can contribute strongly to gene guideline, research shows Kumar Jeetendra | April 22, 2021 A group of scientists from Russia studied the function of double-stranded fragments of the aging RNA and revealed that the interaction between distant areas of the RNA can modulate gene expression. The study was published in Nature Communications. At school, we learn that DNA is double-stranded and RNA is single-stranded, but that isn’t entirely true. …
Novel platform has potential to detect many disease-related biomarkers in just one test Kumar Jeetendra | April 28, 2021 Most conventional molecular diagnostics usually detect only one disease-related biomarker. Fantastic examples are the PCR tests now used to diagnose COVID-19 by detecting a particular sequence from SARS-CoV-2. Such so-called singleplex methods give reliable results because they are”calibrated” to a single biomarker. However, determining whether a patient is infected with a new SARS-CoV-2 version or …
Researchers develop experimental direct-acting antiviral treatment to treat COVID-19 Kumar Jeetendra | May 18, 2021 An international team of scientists from the Menzies Health Institute Queensland (MHIQ) at Griffith University and from City of Hope, a research and treatment center for cancer, diabetes and other life-threatening diseases in the U.S., have developed an experimental direct-acting antiviral therapy to treat COVID-19. Conventional antivirals reduce symptoms and help people recover earlier. Examples …
New testing protocols for SARS-CoV-2 can handle a huge number of tests inside 48 hours Kumar Jeetendra | May 25, 2021 Researchers in the Vienna BioCenter designed a testing protocol for SARS-CoV-2 that can process tens of thousands of samples in less than 48 hours. The method, called SARSeq, is printed in the journal Nature Communications and might be adapted to many more pathogens. The COVID-19 pandemic has lasted more than a year and continues to …
Analysts study the role of subnuclear NSrp70 in T cell-intervened adaptive immunity Kumar Jeetendra | July 15, 2021 T cell are part of the body’s immune response. The way proteins are spliced in their development and maturation determines how T cells can recognize different pathogens and mount defense against them. Scientists from Korea now highlight the role of NSrp70 in regulating maturation. This protein was previously found in T cells subnuclear space and …
Scientists test a library of lipid-based compounds to empower safe RNA drug delivery to Lungs Kumar Jeetendra | July 30, 2021 Japan’s Hokkaido University researchers created and tested a collection of lipid-based compounds in order to deliver RNA drugs safely and effectively to the lungs. The findings were published in Materials Horizons. The COVID-19 pandemic response made it all more familiar with RNA vaccines. These vaccines carry genetic code into the cells, which triggers the production …
New system joins PC programming and cryo-EM to decide 3D constructions of RNA-only molecules Kumar Jeetendra | August 16, 2021 The single-stranded gene material RNA, also known as RNA, is most well-known for its ability to guide the assembly of proteins and carry the genetic code for viruses such as HIV and SARS-CoV-2. Scientists discovered a hidden talent 40 years ago: It can catalyze chemical reaction in cells, including joining and snipping RNA strands. This …
Small molecule drug can weaken the triggers of neuroinflammation, preclinical review shows Kumar Jeetendra | September 24, 2021 Neuroinflammation may cause worse outcomes in cases of stroke, injuries to the brain or injury, and can increase the severity of neurodegenerative diseases such as ALS, Parkinson’s, or Alzheimer’s. This suggests that reducing neuroinflammation might be an exciting new method to treat neurological disorders and neuropathic pain caused by neuroinflammation. In a preclinical study , …
Novel antibody candidate shows powerful binding to different SARS-CoV-2 variant mutations Kumar Jeetendra | September 25, 2021 Twist Bioscience Corporation today reported that its internally-discovered antibody candidate TB202-3 (CoVIC-094), demonstrated potent binding to diverse SARS-CoV-2 variant mutations, including strains with the E484K, N501Y, D614G, Y453F and K417N mutations in pseudovirus assays, indicating this therapeutic antibody may be effective in treating many strains of COVID-19. The Coronavirus Immunotherapy Consortium (CoVIC) is an academic-industry-non-profit …
New technique to make a modest and rapid COVID-19 test dependent on isothermal amplification Kumar Jeetendra | December 30, 2021 Russian researchers have devised the method to make an affordable and quick COVID-19 test that relies on isothermal amplifying. According to their paper in Applied Biochemistry and Microbiology The using this method can allow researchers to create universal test methods for any COVID-19 variations. There are many options for devices that detect the presence of SARS-CoV-2 within human …
Significance of Nucleotides in Genome, Genetics and Molecular biology & Biochemistry Kumar Jeetendra | July 12, 2023 Nucleotides are the building blocks of nucleic acids, which include DNA and RNA. Their relevance in genome is enormous, and they play a crucial role in genetics and molecular biology. Here are the important characteristics of nucleotides and their significance: Genetic Information: Nucleotides act as the carriers of genetic information. Adenine, Guanine, Cytosine, or Thymine …
