Biomarkers can foresee how hereditarily identical cells act distinctively under pressure Kumar Jeetendra | January 10, 2021 A set of biomarkers not traditionally associated with cell fate can accurately forecast how genetically identical cells behave differently under pressure, according to a UT Southwestern study. The findings, published by Cell Reports as a Dec. 1 cover story, could eventually result in more predictable responses to pharmaceutical remedies. Groups of the same types of …
New fluorescence microscopy strategy produces nanoscale 3D pictures of living cells Kumar Jeetendra | January 12, 2021 A new fluorescence microscopy technique has produced the world’s first nanoscale 3D images of molecules in a whole, living cell, researchers at KTH Royal Institute of Technology reported. Ilaria Testa, an associate professor at KTH and researcher at the Science for Life Laboratory, says the technique is capable of generating images with precision that until …
Boosting a characteristic cell cycle could bring down ventilator-related lung damage Kumar Jeetendra | January 12, 2021 An unfortunate truth about the use of mechanical ventilation to save the lives of patients in respiratory distress is that the pressure used to inflate the lungs is very likely to cause further lung damage. In a new study, scientists identified a molecule that’s produced by immune cells during mechanical ventilation to try to decrease …
Analysts recognize interface among ALS and collection of DNA-RNA hybrids in the genome Kumar Jeetendra | January 13, 2021 Researchers from the University of Seville and the University of Pavia have identified a connection between Amyotrophic Lateral Sclerosis (ALS) and the accumulation of DNA-RNA hybrids in the genome. The accumulation of these hybrids causes increased genomic damage and boosts genetic instability. This finding will make it possible to better understand the molecular basis of …
UH scientist attempting to recognize likely new therapeutic target for kidney sickness Kumar Jeetendra | January 14, 2021 In the past year, high serum suPAR levels also have been found to predict kidney and multiple organ failure in hospitalized patients with COVID-19. “FSGS is a particularly insidious kidney disease. In many patients, it inexorably leads to kidney failure and we don’t have much to offer to stop it, and worse still, in most …
National consortium to examine the impacts of arising SARS-CoV-2 mutations Kumar Jeetendra | January 16, 2021 The’G2P-UK’ National Virology Consortium will study how mutations in the virus affect key outcomes like how transmissible it is, the seriousness of COVID-19 it causes, and the potency of vaccines and treatments. The Consortium will bring together leading virologists from 10 research institutions. They will work together with the COVID-19 Genomics UK (COG-UK) consortium, which …
Research finds new proof about the systems controlling skin repair and regeneration Kumar Jeetendra | January 19, 2021 As the air continues to dry and temperatures drop, the yearly battle against dry hands and skin has officially begun. New research from Northwestern University has discovered new evidence deep within the skin about the mechanisms controlling skin renewal and repair. Skin’s barrier function gives it the unique ability to fight winter woes and keep …
Scientists find uncommon hereditary disorder that influences the brain, heart and facial highlights Kumar Jeetendra | January 21, 2021 Researchers at the National Institutes of Health have discovered a new genetic disorder characterized by developmental delays and malformations of the brain, heart and facial features. Named linkage-specific-deubiquitylation-deficiency-induced embryonic defects syndrome (LINKED), it is caused by a mutated version of the OTUD5 gene, which interferes with key molecular actions in embryo development. The findings indicate …
World’s first completely reversible control of the circadian clock Kumar Jeetendra | January 26, 2021 The Nagoya University Institute of Transformative Bio-Molecules (WPI-ITbM) research team of Designated Associate Professor Tsuyoshi Hirota, Postdoctoral Fellow Simon Miller, Professor Kenichiro Itami and grad student Tsuyoshi Oshima (Research Fellowship for Young Scientists, JSPS), in collaboration with the team of Professor Ben Feringa and Postdoctoral Fellow Dušan Kolarski of Groningen University in the Netherlands, have …
Study shows why children of obese moms have inclination to create metabolic illnesses Kumar Jeetendra | January 27, 2021 A Brazilian study published in the journal Molecular Human Reproduction helps understand why overweight mothers often have children with a propensity to develop metabolic disease during their lifetime, according to previous research. According to the authors,”transgenerational transmission of metabolic disorders” may be associated with Mfn2 deficiency in the mother’s oocytes (immature eggs). Mfn2 refers to …
Substances in tick spit actuate insusceptible reaction smothering proteins in cattles Kumar Jeetendra | January 28, 2021 Scientists from Hokkaido University, Japan and Universidade Federal do Rio Grande do Sul and Universidade Federal do Rio de Janeiro, Brazil, have revealed that substances in tick saliva trigger immune response-suppressing proteins in cows that facilitates the transmission of tick-borne diseases. The finding was published in the journal Scientific Reports and could assist in the …
New gene based vaccine procedure gets award from the Bill and Melinda Gates Foundation Kumar Jeetendra | January 29, 2021 The AAVCOVID vaccine application, a novel gene-based vaccine plan that utilizes an adeno-associated virus (AAV) vector, was granted an award for up to $2.1 million from the Bill & Melinda Gates Foundation. The grant will assist the effort to bring further preclinical validation into the AAV vaccine platform. An AAVCOVID vaccine candidate is set to …
